Cysteine-conjugate transaminase
cysteine-conjugate transaminase | |||||||||
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Identifiers | |||||||||
EC number | 2.6.1.75 | ||||||||
CAS number | 117698-05-2 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / EGO | ||||||||
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In enzymology, a cysteine-conjugate transaminase (EC 2.6.1.75) is an enzyme that catalyzes the chemical reaction
- S-(4-bromophenyl)-L-cysteine + 2-oxoglutarate S-(4-bromophenyl)mercaptopyruvate + L-glutamate
Thus, the two substrates of this enzyme are S-(4-bromophenyl)-L-cysteine and 2-oxoglutarate, whereas its two products are S-(4-bromophenyl)mercaptopyruvate and L-glutamate.
This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is S-(4-bromophenyl)-L-cysteine:2-oxoglutarate aminotransferase. Other names in common use include cysteine conjugate aminotransferase, and cysteine-conjugate alpha-ketoglutarate transaminase (CAT-1).
References
- Tateishi M; Ichimoto, N; Takanohashi, Y; Ichihara, S; Fukazawa, H; Tateishi, M (1988). "Purification and characterization of cysteine conjugate transaminases from rat liver". Xenobiotica. 18 (9): 1015–28. doi:10.3109/00498258809042224. PMID 2852419.
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