FUT9

FUT9
Identifiers
Aliases FUT9, Fuc-TIX, fucosyltransferase 9
External IDs MGI: 1330859 HomoloGene: 4800 GeneCards: FUT9
RNA expression pattern
More reference expression data
Orthologs
Species Human Mouse
Entrez

10690

14348

Ensembl

ENSG00000172461

ENSMUSG00000055373

UniProt

Q9Y231

O88819

RefSeq (mRNA)

NM_006581

NM_010243

RefSeq (protein)

NP_006572.2

NP_034373.1

Location (UCSC) Chr 6: 96.02 – 96.22 Mb Chr 4: 25.61 – 25.8 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

Alpha-(1,3)-fucosyltransferase is an enzyme that in humans is encoded by the FUT9 gene.[3][4][5]

FUT9 is one of several alpha-3-fucosyltransferases that can catalyze the last step in the biosynthesis of Lewis antigen, the addition of a fucose to precursor polysaccharides. FUT9 synthesizes the LeX oligosaccharide (CD15), which is expressed in organ buds progressing in mesenchyma during human embryogenesis.[supplied by OMIM][5]

References

  1. "Human PubMed Reference:".
  2. "Mouse PubMed Reference:".
  3. Kaneko M, Kudo T, Iwasaki H, Ikehara Y, Nishihara S, Nakagawa S, Sasaki K, Shiina T, Inoko H, Saitou N, Narimatsu H (Jul 1999). "Alpha1,3-fucosyltransferase IX (Fuc-TIX) is very highly conserved between human and mouse; molecular cloning, characterization and tissue distribution of human Fuc-TIX". FEBS Lett. 452 (3): 237–42. doi:10.1016/S0014-5793(99)00640-7. PMID 10386598.
  4. Kaneko M, Kudo T, Iwasaki H, Shiina T, Inoko H, Kozaki T, Saitou N, Narimatsu H (Jan 2000). "Assignment of the human alpha 1,3-fucosyltransferase IX gene (FUT9) to chromosome band 6q16 by in situ hybridization". Cytogenet Cell Genet. 86 (3–4): 329–30. doi:10.1159/000015329. PMID 10575236.
  5. 1 2 "Entrez Gene: FUT9 fucosyltransferase 9 (alpha (1,3) fucosyltransferase)".

Further reading


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