Glycine N-phenylacetyltransferase

Glycine N-phenylacetyltransferase
Identifiers
EC number 2.3.1.192
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Glycine N-phenylacetyltransferase (EC 2.3.1.192, arylacetyl-CoA N-acyltransferase, arylacetyltransferase, GAT (gene)) is an enzyme with systematic name phenylacetyl-CoA:glycine N-phenylacetyltransferase.[1][2][3] This enzyme catalyses the following chemical reaction

phenylacetyl-CoA + glycine CoA + phenylacetylglycine

This enzyme was purified from bovine liver mitochondria.

References

  1. Nandi, D.L.; Lucas, S.V.; Webster, L.T. (1979). "Benzoyl-coenzyme A:glycine N-acyltransferase and phenylacetyl-coenzyme A:glycine N-acyltransferase from bovine liver mitochondria. Purification and characterization". J. Biol. Chem. 254: 7230–7237. PMID 457678.
  2. Kelley, M.; Vessey, D.A. (1990). "The effects of ions on the conjugation of xenobiotics by the aralkyl-CoA and arylacetyl-CoA N-acyltransferases from bovine liver mitochondria". J. Biochem. Toxicol. 5: 125–135. doi:10.1002/jbt.2570050208. PMID 2283662.
  3. Vessey, D.A.; Lau, E. (1998). "Determination of the sequence of the arylacetyl acyl-CoA:amino acid N-acyltransferase from bovine liver mitochondria and its homology to the aralkyl acyl-CoA:amino acid N-acyltransferase". J. Biochem. Mol. Toxicol. 12: 275–279. doi:10.1002/(sici)1099-0461(1998)12:5<275::aid-jbt3>3.0.co;2-i. PMID 9664233.
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