Isopropyl nitrite

Isopropyl nitrite
Clinical data
ATC code None
Identifiers
Synonyms Isopropyl alcohol nitrite; nitrous acid, isopropyl ester; 1-methylethyl nitrite; 2-propyl nitrite
CAS Number 541-42-4 YesY
PubChem (CID) 10929
ChemSpider 10466 YesY
ECHA InfoCard 100.007.982
Chemical and physical data
Formula C3H7NO2
Molar mass 89.09
3D model (Jmol) Interactive image
Density 0.8684 g/cm3
Boiling point 40 °C (104 °F)
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The chemical compound isopropyl nitrite (or 2-propyl nitrite) is an alkyl nitrite made from isopropanol. It is a clear pale yellow oil.[1]

Applications

Isopropyl nitrite is one of the compounds used as poppers, an inhalant drug that induces a brief euphoria. Isopropyl nitrite has largely replaced Isobutyl nitrite in poppers.

Safety

Has been associated with Eye Maculopathy visual impairment with central scotomata, associated to bilateral foveal yellow spots and IS/OS junction disruption.[2]

References

  1. Handbook of Chemistry and Physics, CRC Press, 85th edition
  2. Davies, AJ; Kelly, SP; Naylor, SG; Bhatt, PR; Mathews, JP; Sahni, J; Haslett, R; McKibbin, M (2012). "Adverse ophthalmic reaction in poppers users: case series of 'poppers maculopathy'". Eye (Lond). 26: 1479–86. doi:10.1038/eye.2012.191. PMC 3496104Freely accessible. PMID 23079752.


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