Pheophorbide a oxygenase
| Pheophorbide a oxygenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 1.14.15.17 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Pheophorbide A oxygenase (EC 1.14.15.17, pheide a monooxygenase, pheide a oxygenase, PAO) is an enzyme with systematic name pheophorbide-a,NADPH:oxygen oxidoreductase (biladiene-forming).[1][2][3][4][5][6] This enzyme catalyses the following chemical reaction
- Pheophorbide A + NADPH + H+ + O2 red chlorophyll catabolite + NADP+
Pheophorbide A oxygenase participates in chlorophyll degradation.
References
- ↑ Hörtensteiner, S.; Wüthrich, K.L.; Matile, P.; Ongania, K.H.; Kräutler, B. (1998). "The key step in chlorophyll breakdown in higher plants. Cleavage of pheophorbide a macrocycle by a monooxygenase". J. Biol. Chem. 273 (25): 15335–15339. doi:10.1074/jbc.273.25.15335. PMID 9624113.
- ↑ Pruzinská, A.; Tanner, G.; Anders, I.; Roca, M.; Hörtensteiner, S. (2003). "Chlorophyll breakdown: pheophorbide a oxygenase is a Rieske-type iron-sulfur protein, encoded by the accelerated cell death 1 gene". Proc. Natl. Acad. Sci. USA. 100 (25): 15259–15264. doi:10.1073/pnas.2036571100. PMC 299977
. PMID 14657372. - ↑ Chung, D.W.; Pružinská, A.; Hörtensteiner, S.; Ort, D.R. (2006). "The role of pheophorbide a oxygenase expression and activity in the canola green seed problem". Plant Physiol. 142 (1): 88–97. doi:10.1104/pp.106.084483. PMC 1557622. PMID 16844830.
- ↑ Rodoni, S.; Mühlecker, W.; Anderl, M.; Kräutler, B.; Moser, D.; Thomas, H.; Matile, P.; Hörtensteiner, S. (1997). "Chlorophyll breakdown in senescent chloroplasts. Cleavage of pheophorbide a in two enzymic steps". Plant Physiol. 115 (2): 669–676. doi:10.1104/pp.115.2.669. PMC 158527. PMID 12223835.
- ↑ Hörtensteiner, S. (2006). "Chlorophyll degradation during senescence". Annu. Rev. Plant Biol. 57: 55–77. doi:10.1146/annurev.arplant.57.032905.105212. PMID 16669755.
- ↑ Pružinská, A.; Anders, I.; Aubry, S.; Schenk, N.; apernoux-Lüthi, E.; Müller, T.; Kräutler, B.; Hörtensteiner, S. (2007). "In vivo participation of red chlorophyll catabolite reductase in chlorophyll breakdown". Plant Cell. 19 (1): 369–387. doi:10.1105/tpc.106.044404. PMC 1820978. PMID 17237353.
External links
- Pheophorbide a oxygenase at the US National Library of Medicine Medical Subject Headings (MeSH)
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