Presqualene diphosphate synthase

Presqualene diphosphate synthase
Identifiers
EC number 2.5.1.103
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Presqualene diphosphate synthase (EC 2.5.1.103, SSL-1 (gene)) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate:(2E,6E)-farnesyl-diphosphate farnesyltransferase (presqualene diphosphate forming).[1] This enzyme catalyses the following chemical reaction

2 (2E,6E)-farnesyl diphosphate presqualene diphosphate + diphosphate

This enzyme is isolated from the green alga Botryococcus braunii BOT22.

References

  1. Niehaus TD, Okada S, Devarenne TP, Watt DS, Sviripa V, Chappell J (2011). "Identification of unique mechanisms for triterpene biosynthesis in Botryococcus braunii". Proc. Natl. Acad. Sci. USA. 108 (30): 12260–12265. doi:10.1073/pnas.1106222108. PMC 3145686Freely accessible. PMID 21746901.
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