Salutaridinol 7-O-acetyltransferase
salutaridinol 7-O-acetyltransferase | |||||||||
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Identifiers | |||||||||
EC number | 2.3.1.150 | ||||||||
CAS number | 156859-13-1 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / EGO | ||||||||
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In enzymology, a salutaridinol 7-O-acetyltransferase (EC 2.3.1.150) is an enzyme that catalyzes the chemical reaction
- acetyl-CoA + salutaridinol CoA + 7-O-acetylsalutaridinol
Thus, the two substrates of this enzyme are acetyl-CoA and salutaridinol, whereas its two products are CoA and 7-O-acetylsalutaridinol.
This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-CoA:salutaridinol 7-O-acetyltransferase. This enzyme participates in alkaloid biosynthesis i.
References
- Lenz R, Zenk MH (1994). "Closure of the oxide bridge in morphine biosynthesis". Tetrahedron Lett. 35 (23): 3897–3900. doi:10.1016/S0040-4039(00)76696-2.
- Lenz R, Zenk MH (1995). "Acetyl coenzyme A:salutaridinol-7-O-acetyltransferase from papaver somniferum plant cell cultures. The enzyme catalyzing the formation of thebaine in morphine biosynthesis". J. Biol. Chem. 270 (52): 31091–6. doi:10.1074/jbc.270.52.31091. PMID 8537369.
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