Samatya (Greek: Ψαμάθεια, pr. Psamatheia; Armenian: Սամաթիա) is a neighborhood of the Fatih district of Istanbul. It is located along the Marmara Sea, and borders to the west on the neighborhood of Yedikule (the "Castle of the Seven Towers").
About 383 AD, the first monastic institution was established in Constantinople, at Psamatheia, at that time still outside the walled city.
Up to recent times, Samatya was mostly inhabited by Armenians, who were settled here in 1458 by Sultan Mehmet II, and who own there the church of Surp Kevork, also called Sulu Manastiri (Water's monastery) – previously an Eastern Orthodox church which dates back to before the Ottoman conquest, and by Greeks, who have the churches of Hristos Analipsis and Haghios Menas.
In Samatya there is also an important public hospital, the İstanbul Eğitim ve Araştırma Hastanesi.
One of the most picturesque fish markets of Istanbul is placed in the quarter, just opposite the train station.
- Hrachia Adjarian - Armenian linguist
- Simon Agopyan - Armenian painter
- Mihran Apikyan - Armenian writer and linguist
- Levon Larents - Armenian writer
- Janin, Raymond (1964). Constantinople Byzantine (in French) (2 ed.). Paris: Institut Français d'Etudes Byzantines.
- Müller-Wiener, Wolfgang (1977). Bildlexikon zur Topographie Istanbuls: Byzantion, Konstantinupolis, Istanbul bis zum Beginn d. 17 Jh (in German). Tübingen: Wasmuth. ISBN 978-3-8030-1022-3.