Sulfamethoxypyridazine

Sulfamethoxypyridazine
Clinical data

AHFS/Drugs.com	International Drug Names
ATC code	J01ED05 (WHO) QJ01EQ15 (WHO)
Identifiers
IUPAC name 4-amino-N-(6-methoxypyridazin-3-yl)benzenesulfonamide
CAS Number	80-35-3^N
PubChem (CID)	5330
ChemSpider	5139^Y
UNII	T034E4NS2Z^Y
KEGG	D02439^Y
ChEBI	CHEBI:102516^Y
ChEMBL	CHEMBL268869^Y
ECHA InfoCard	100.001.157
Chemical and physical data
Formula	C₁₁H₁₂N₄O₃S
Molar mass	280.304 g/mol
3D model (Jmol)	Interactive image
SMILES O=S(=O)(Nc1nnc(OC)cc1)c2ccc(N)cc2
InChI InChI=1S/C11H12N4O3S/c1-18-11-7-6-10(13-14-11)15-19(16,17)9-4-2-8(12)3-5-9/h2-7H,12H2,1H3,(H,13,15)^Y Key:VLYWMPOKSSWJAL-UHFFFAOYSA-N^Y
^NY (what is this?) (verify)

Sulfamethoxypyridazine is a sulfonamide antibacterial.

It is prescribed for vaginal irritation, and severe acute thrush.

It is also used in the treatment of Dermatitis herpetiformis, where it is an alternative therapy to Dapsone.

Sulfamethoxypyridazine is supplied as 500mg tablets.

Antifolates
(inhibits
purine metabolism,
thereby inhibiting
DNA and RNA synthesis)

Short- acting	Sulfaisodimidine Sulfamethizole Sulfadimidine Sulfapyridine Sulfafurazole Sulfanilamide Prontosil Sulfathiazole Sulfathiourea

Intermediate- acting	Sulfamethoxazole Sulfadiazine^# Sulfamoxole

Long- acting	Sulfadimethoxine Sulfadoxine Sulfalene Sulfametomidine Sulfametoxydiazine Sulfamethoxypyridazine Sulfaperin Sulfamerazine Sulfaphenazole Sulfamazone

Other/ungrouped	Sulfacetamide Sulfadicramide Sulfametrole

Combinations

2nd g.	Ciprofloxacin^# Ofloxacin Enoxacin^‡ Fleroxacin^‡ Lomefloxacin^‡ Nadifloxacin^‡ Norfloxacin^‡ Pefloxacin^‡ Rufloxacin^‡

3rd g.	Levofloxacin Balofloxacin^‡ Grepafloxacin^‡ Pazufloxacin^‡ Sparfloxacin^‡ Temafloxacin^‡ Tosufloxacin^‡

4th g.	Besifloxacin Gatifloxacin Finafloxacin Gemifloxacin Moxifloxacin Clinafloxacin^† Garenoxacin^‡ Prulifloxacin^‡ Sitafloxacin^‡ Trovafloxacin^‡/Alatrofloxacin^‡

Vet.	Danofloxacin Difloxacin Enrofloxacin Ibafloxacin Marbofloxacin Orbifloxacin Pradofloxacin Sarafloxacin

Newer non-fluorinated

Related (DG)

Nitro- imidazole derivatives	Metronidazole^# Tinidazole Ornidazole

Nitrofuran derivatives	Nitrofurantoin^# Furazolidone^‡ Nifurtoinol

RNA synthesis

Rifamycins/ RNA polymerase	Rifampicin^# Rifabutin Rifapentine Rifaximin Rifalazil^§

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