UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine transaminase

UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine transaminase
Identifiers
EC number	2.6.1.92
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine transaminase (EC 2.6.1.92, PseC) is an enzyme with systematic name UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine:2-oxoglutarate aminotransferase.^[1][2] This enzyme catalyses the following chemical reaction

UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine + 2-oxoglutarate $\rightleftharpoons$ UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hex-4-ulose + L-glutamate

This enzyme is a pyridoxal-phosphate protein.

References

1. Schoenhofen, I.C.; McNally, D.J.; Vinogradov, E.; Whitfield, D.; Young, N.M.; Dick, S.; Wakarchuk, W.W.; Brisson, J.R.; Logan, S.M. (2006). "Functional characterization of dehydratase/aminotransferase pairs from Helicobacter and Campylobacter: enzymes distinguishing the pseudaminic acid and bacillosamine biosynthetic pathways". J. Biol. Chem. 281: 723–732. doi:10.1074/jbc.m511021200. PMID 16286454.
2. Schoenhofen, I.C.; Lunin, V.V.; Julien, J.P.; Li, Y.; Ajamian, E.; Matte, A.; Cygler, M.; Brisson, J.R.; Aubry, A.; Logan, S.M.; Bhatia, S.; Wakarchuk, W.W.; Young, N.M. (2006). "Structural and functional characterization of PseC, an aminotransferase involved in the biosynthesis of pseudaminic acid, an essential flagellar modification in Helicobacter pylori". J. Biol. Chem. 281: 8907–8916. doi:10.1074/jbc.m512987200. PMID 16421095.

External links

• UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine transaminase at the US National Library of Medicine Medical Subject Headings (MeSH)