WASF3

WASF3
Identifiers
Aliases WASF3, Brush-1, SCAR3, WAVE3, WAS protein family member 3
External IDs MGI: 2658986 HomoloGene: 68527 GeneCards: WASF3
RNA expression pattern
More reference expression data
Orthologs
Species Human Mouse
Entrez

10810

245880

Ensembl

ENSG00000132970

ENSMUSG00000029636

UniProt

Q9UPY6
Q5T8P4

Q8VHI6

RefSeq (mRNA)

NM_001291965
NM_006646

NM_145155

RefSeq (protein)

NP_001278894.1
NP_006637.2
NP_006637.2

NP_660137.1

Location (UCSC) Chr 13: 26.56 – 26.69 Mb Chr 5: 146.38 – 146.47 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

Wiskott-Aldrich syndrome protein family member 3 is a protein that in humans is encoded by the WASF3 gene.[3][4]

This gene encodes a member of the Wiskott-Aldrich syndrome protein family. The gene product is a protein that forms a multiprotein complex that links receptor kinases and actin. Binding to actin occurs through a C-terminal verprolin homology domain in all family members. The multiprotein complex serves to tranduce signals that involve changes in cell shape, motility or function.[4]

References

  1. "Human PubMed Reference:".
  2. "Mouse PubMed Reference:".
  3. Suetsugu S, Miki H, Takenawa T (Jul 1999). "Identification of two human WAVE/SCAR homologues as general actin regulatory molecules which associate with the Arp2/3 complex". Biochem Biophys Res Commun. 260 (1): 296–302. doi:10.1006/bbrc.1999.0894. PMID 10381382.
  4. 1 2 "Entrez Gene: WASF3 WAS protein family, member 3".

Further reading


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