Zeaxanthin epoxidase

Zeaxanthin epoxidase
Identifiers
EC number 1.14.13.90
CAS number 149718-34-3
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Zeaxanthin epoxidase (EC 1.14.13.90, Zea-epoxidase) is an enzyme with systematic name zeaxanthin,NAD(P)H:oxygen oxidoreductase.[1][2][3][4][5][6][7] This enzyme catalyses the following chemical reaction

zeaxanthin + 2 NAD(P)H + 2 H+ + 2 O2 violaxanthin + 2 NAD(P)+ + 2 H2O (overall reaction)
(1a) zeaxanthin + NAD(P)H + H+ + O2 antheraxanthin + NAD(P)+ + H2O
(1b) antheraxanthin + NAD(P)H + H+ + O2 violaxanthin + NAD(P)+ + H2O

Zeaxanthin epoxidase is a flavoprotein (FAD) that is active under conditions of low light.

References

  1. Buch, K.; Stransky, H.; Hager, A. (1995). "FAD is a further essential cofactor of the NAD(P)H and O2-dependent zeaxanthin-epoxidase". FEBS Lett. 376 (1-2): 45–48. doi:10.1016/0014-5793(95)01243-9. PMID 8521963.
  2. Bugos, R.C.; Hieber, A.D.; Yamamoto, H.Y. (1998). "Xanthophyll cycle enzymes are members of the lipocalin family, the first identified from plants". J. Biol. Chem. 273 (25): 15321–15324. doi:10.1074/jbc.273.25.15321. PMID 9624110.
  3. Thompson, A.J.; Jackson, A.C.; Parker, R.A.; Morpeth, D.R.; Burbidge, A.; Taylor, I.B. (2000). "Abscisic acid biosynthesis in tomato: regulation of zeaxanthin epoxidase and 9-cis-epoxycarotenoid dioxygenase mRNAs by light/dark cycles, water stress and abscisic acid". Plant Mol. Biol. 42 (6): 833–845. doi:10.1023/A:1006448428401. PMID 10890531.
  4. Hieber, A.D.; Bugos, R.C.; Yamamoto, H.Y. (2000). "Plant lipocalins: violaxanthin de-epoxidase and zeaxanthin epoxidase". Biochim. Biophys. Acta. 1482 (1-2): 84–91. doi:10.1016/s0167-4838(00)00141-2. PMID 11058750.
  5. Frommolt, R.; Goss, R.; Wilhelm, C. (2001). "The de-epoxidase and epoxidase reactions of Mantoniella squamata (Prasinophyceae) exhibit different substrate-specific reaction kinetics compared to spinach". Planta. 213 (3): 446–456. doi:10.1007/s004250100589. PMID 11506368.
  6. Frommolt, R.; Goss, R.; Wilhelm, C. (2001). "Erratum Report. The de-epoxidase and epoxidase reactions of Mantoniella squamata (Prasinophyceae) exhibit different substrate-specific reaction kinetics compared to spinach". Planta. 213 (3): 492–492. doi:10.1007/s004250100619.
  7. Matsubara, S.; Morosinotto, T.; Bassi, R.; Christian, A.L.; Fischer-Schliebs, E.; Luttge, U.; Orthen, B.; Franco, A.C.; Scarano, F.R.; Forster, B.; Pogson, B.J.; Osmond, C.B. (2003). "Occurrence of the lutein-epoxide cycle in mistletoes of the Loranthaceae and Viscaceae". Planta. 217 (6): 868–879. doi:10.1007/s00425-003-1059-7. PMID 12844265.
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