D-ribitol-5-phosphate cytidylyltransferase
D-ribitol-5-phosphate cytidylyltransferase | |||||||||
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Identifiers | |||||||||
EC number | 2.7.7.40 | ||||||||
CAS number | 9027-07-0 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / EGO | ||||||||
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In enzymology, a D-ribitol-5-phosphate cytidylyltransferase (EC 2.7.7.40) is an enzyme that catalyzes the chemical reaction
- CTP + D-ribitol 5-phosphate diphosphate + CDP-ribitol
Thus, the two substrates of this enzyme are CTP and D-ribitol 5-phosphate, whereas its two products are diphosphate and CDP-ribitol.
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). The systematic name of this enzyme class is CTP:D-ribitol-5-phosphate cytidylyltransferase. Other names in common use include CDP ribitol pyrophosphorylase, cytidine diphosphate ribitol pyrophosphorylase, ribitol 5-phosphate cytidylyltransferase, and cytidine diphosphoribitol pyrophosphorylase. This enzyme participates in pentose and glucuronate interconversions.
References
- Shaw DRD (1962). "Pyrophosphorolysis and enzymic synthesis of cytidine diphosphate glycerol and cytidine diphosphate ribitol". Biochem. J. 82: 297–312. PMC 1243453. PMID 13911452.