Formate kinase
formate kinase | |||||||||
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Identifiers | |||||||||
EC number | 2.7.2.6 | ||||||||
CAS number | 9026-65-7 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / EGO | ||||||||
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In enzymology, a formate kinase (EC 2.7.2.6) is an enzyme that catalyzes the chemical reaction
- ATP + formate ADP + formyl phosphate
Thus, the two substrates of this enzyme are ATP and formate, whereas its two products are ADP and formyl phosphate.
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with a carboxy group as acceptor. The systematic name of this enzyme class is ATP:formate phosphotransferase. This enzyme participates in glyoxylate and dicarboxylate metabolism.
References
- Sly WS; Stadtman ER (1963). "Formate metabolism. II. Enzymatic synthesis of formyl phosphate and formyl coenzyme A in Clostridium cylindrosporum". J. Biol. Chem. 238: 2639–2647.
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