Interleukin-12 receptor
| interleukin 12 receptor, beta 1 | |
|---|---|
| Identifiers | |
| Symbol | IL12RB1 |
| Alt. symbols | IL12RB, CD212 |
| Entrez | 3594 |
| HUGO | 5971 |
| OMIM | 601604 |
| RefSeq | NM_005535 |
| UniProt | P42701 |
| Other data | |
| Locus | Chr. 19 p13.1 |
| beta 2 subunit, interleukin 12 receptor, beta 2 | |
|---|---|
| Identifiers | |
| Symbol | IL12RB2 |
| Entrez | 3595 |
| HUGO | 5972 |
| OMIM | 601642 |
| RefSeq | NM_001559 |
| UniProt | Q99665 |
| Other data | |
| Locus | Chr. 1 p31.3-31.2 |
Interleukin 12 receptor is a type I cytokine receptor, binding interleukin 12. It consists of beta 1[1] and beta 2 subunits.[2]
References
- ↑ Chua AO, Chizzonite R, Desai BB, Truitt TP, Nunes P, Minetti LJ, Warrier RR, Presky DH, Levine JF, Gately MK (1994). "Expression cloning of a human IL-12 receptor component. A new member of the cytokine receptor superfamily with strong homology to gp130". J. Immunol. 153 (1): 128–36. PMID 7911493.
- ↑ Presky DH, Yang H, Minetti LJ, Chua AO, Nabavi N, Wu CY, Gately MK, Gubler U (1996). "A functional interleukin 12 receptor complex is composed of two beta-type cytokine receptor subunits". Proc. Natl. Acad. Sci. U.S.A. 93 (24): 14002–14007. doi:10.1073/pnas.93.24.14002. PMC 19484
. PMID 8943050.
External links
- Receptors, Interleukin-12 at the US National Library of Medicine Medical Subject Headings (MeSH)
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