Iron pentacarbonyl
5.png) | |
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| Names | |
|---|---|
| IUPAC name
pentacarbonyliron | |
| Other names
Pentacarbonyl iron Iron carbonyl | |
| Identifiers | |
13463-40-6  | |
| 3D model (Jmol) | Interactive image |
| ChEBI | CHEBI:30251 |
| ChemSpider | 24254 |
| ECHA InfoCard | 100.033.323 |
| PubChem | 26040 |
| RTECS number | NO4900000 |
| UNII | 6WQ62TAQ6Z |
| UN number | 1994 |
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| Properties | |
| Fe(CO)5 | |
| Molar mass | 195.90 g/mol |
| Appearance | straw-yellow liquid |
| Odor | musty |
| Density | 1.453 g/cm3 |
| Melting point | −21.0 °C (−5.8 °F; 252.2 K) |
| Boiling point | 103 °C (217 °F; 376 K) |
| Insoluble | |
| Solubility | Soluble in organic solvents slightly soluble in alcohol insoluble in ammonia |
| Vapor pressure | 40 mmHg (30.6 °C)[1] |
| Refractive index (nD) |
1.5196 (20 °C) |
| Structure | |
| D3h | |
| trigonal bipyramidal | |
| trigonal bipyramidal | |
| 0 D | |
| Hazards | |
| Main hazards | Very toxic, highly flammable |
| Safety data sheet | ICSC 0168 |
| EU classification (DSD) |
  |
| NFPA 704 | |
| Flash point | −15 °C (5 °F; 258 K) |
| 49 °C (120 °F; 322 K) | |
| Explosive limits | 3.7–12.5% |
| Lethal dose or concentration (LD, LC): | |
| LD50 (median dose) |
25 mg/kg (rat, oral) |
| US health exposure limits (NIOSH): | |
| PEL (Permissible) |
none[1] |
| REL (Recommended) |
TWA 0.1 ppm (0.23 mg/m3) ST 0.2 ppm (0.45 mg/m3)[1] |
| IDLH (Immediate danger) |
N.D.[1] |
| Related compounds | |
| Other cations |
Triruthenium dodecacarbonyl Triosmium dodecacarbonyl |
| Related iron carbonyls |
Diiron nonacarbonyl Triiron dodecacarbonyl |
| Related compounds |
Dimanganese decacarbonyl Dicobalt octacarbonyl Nickel tetracarbonyl |
| Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
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| Infobox references | |
Iron pentacarbonyl, also known as iron carbonyl, is the compound with formula Fe(CO)5. Under standard conditions Fe(CO)5 is a free-flowing, straw-colored liquid with a pungent odour. Older samples appear darker. This compound is a common precursor to diverse iron compounds, including many that are useful in small scale organic synthesis.[2]
Properties
Iron pentacarbonyl is one of the homoleptic metal carbonyls; i.e. CO is the only ligand complexed with iron. Other examples include octahedral Cr(CO)6 and tetrahedral Ni(CO)4. Most metal carbonyls have 18 valence electrons, and Fe(CO)5 fits this pattern with 8 valence electrons on Fe and five pairs of electrons provided by the CO ligands. Reflecting its symmetrical structure and charge neutrality, Fe(CO)5 is volatile; it is one of the most frequently encountered liquid metal complexes. Fe(CO)5 adopts a trigonal bipyramidal structure with the Fe atom surrounded by five CO ligands: three in equatorial positions and two axially bound. The Fe–C–O linkages are each linear.
Fe(CO)5 is the archetypal fluxional molecule due to the rapid interchange of the axial and equatorial CO groups via the Berry mechanism on the NMR timescale. Consequently, the 13C NMR spectrum exhibits only one signal due to the rapid interchange between nonequivalent CO sites.
Iron carbonyl is sometimes confused with carbonyl iron, a high-purity metal prepared by decomposition of iron pentacarbonyl.
Synthesis and other iron carbonyls
Fe(CO)5 is produced by the reaction of fine iron particles with carbon monoxide. The compound was described in a journal by Mond and Langer in 1891 as "a somewhat viscous liquid of a pale-yellow colour."[3] Samples were prepared by treatment of finely divided, oxide-free iron powder with carbon monoxide at room temperature.
Industrial synthesis of the compound requires relatively high temperatures and pressures (e.g. 175 atm at 150 °C)[4] as well as special, chemically resistant equipment (e.g. composed of copper-silver alloys). Preparation of the compound at the laboratory scale avoids these complications by using an iodide intermediate:[4]
Fe(CO)5 is sensitive to light. Photodissociation of Fe(CO)5 produces Fe2(CO)9, a yellow-orange solid, also described by Mond. When heated, Fe(CO)5 converts to small amounts of the metal cluster Fe3(CO)12, a green solid. Simple thermolysis, however, is not a useful synthesis, and each iron carbonyl complex exhibits distinct reactivity.
Industrial production and use
The industrial production of this compound is somewhat similar to the Mond process in that the metal is treated with carbon monoxide to give a volatile gas. In the case of iron pentacarbonyl, the reaction is more sluggish. It is necessary to use iron sponge as the starting material, and harsher reaction conditions of 5–30 MPa of carbon monoxide and 150–200 °C. Similar to the Mond process, sulfur acts as a catalyst. The crude iron pentacarbonyl is purified by distillation. Ullmann's Encyclopedia of Industrial Chemistry reports that there are only three plants manufacturing pentacarbonyliron; BASF in Germany and GAF in Alabama have capacities of 9000 and 1500–2000 tonnes/year respectively.[5]
Most iron pentacarbonyl produced is decomposed on site to give pure carbonyl iron in analogy to carbonyl nickel. Some iron pentacarbonyl is burned to give pure iron oxide. Other uses of pentacarbonyliron are small in comparison.[5]
Reactions
CO substitution reactions
Many compounds are derived from Fe(CO)5 by substitution of CO by Lewis bases, L, to give derivatives Fe(CO)5−xLx. Common Lewis bases include isocyanides, tertiary phosphines and arsines, and alkenes. Usually these ligands displace only one or two CO ligands, but certain acceptor ligands such as PF3 and isocyanides can proceed to tetra- and pentasubstitution. These reactions are often induced with a catalyst or light.[6] Illustrative is the synthesis of the bis(triphenylphosphine) complex Fe(CO)3(P(C6H5)3)2.[7] This transformation can be accomplished photochemically, but it is also induced by the addition of NaOH or NaBH4. The catalyst attacks a CO ligand, which labilizes another CO ligand toward substitution. The electrophilicity of Fe(CO)4L is less than that of Fe(CO)5, so the nucleophilic catalyst, disengages and attacks another molecule of Fe(CO)5.
Oxidation and reduction
Most metal carbonyls can be halogenated. Thus, treatment of Fe(CO)5 with halogens gives the ferrous halides Fe(CO)4X2 for X = I, Br, Cl. These species, upon heating lose CO to give the ferrous halides, such as iron(II) chloride.
Reduction of Fe(CO)5 with Na gives Na2Fe(CO)4, "tetracarbonylferrate" also called Collman's reagent. The dianion is isoelectronic with Ni(CO)4 but highly nucleophilic.[8]
Acid-base reactions
Fe(CO)5 is not readily protonated, but it is attacked by hydroxide. Treatment of Fe(CO)5 with aqueous base produces [HFe(CO)4]−, via the Metallacarboxylate intermediate. The oxidation of this monoanion gives triiron dodecarbonyl, Fe3(CO)12. Acidification of solutions of [HFe(CO)4]− gives iron tetracarbonyl hydride, H2Fe(CO)4, the first metal hydride ever reported.
Diene adducts
Dienes react with Fe(CO)5 to give (diene)Fe(CO)3, wherein two CO ligands have been replaced by two olefins. Many dienes undergo this reaction, notably norbornadiene and 1,3-butadiene. One of the more historically significant derivatives is cyclobutadieneiron tricarbonyl (C4H4)Fe(CO)3, where C4H4 is the otherwise unstable cyclobutadiene.[9] Receiving the greatest attention are complexes of the cyclohexadienes, the parent organic 1,4-dienes being available through the Birch reductions. 1,4-Dienes isomerize to the 1,3-dienes upon complexation.[10]
Fe(CO)5 reacts in dicyclopentadiene to form [Fe(C5H5)(CO)2]2, cyclopentadienyliron dicarbonyl dimer. This compound, called "Fp dimer" can be considered a hybrid of ferrocene and Fe(CO)5, although in terms of its reactivity, it resembles neither.
Other uses
In Europe, iron pentacarbonyl was once used as an anti-knock agent in petrol in place of tetraethyllead. Two more modern alternative fuel additives are ferrocene and methylcyclopentadienyl manganese tricarbonyl. Fe(CO)5 is used in the production of "carbonyl iron", a finely divided form of Fe, a material used in magnetic cores of high-frequency coils for radios and televisions and for manufacture of the active ingredients of some radar absorbent materials (e.g. iron ball paint). It is famous as a chemical precursor for the synthesis of various iron-based nanoparticles.
Iron pentacarbonyl has been found to be a strong flame speed inhibitor in oxygen based flames.[11] A few hundred ppm of iron pentacarbonyl are known to reduce the flame speed of stoichiometric methane–air flame by almost 50%. However due to its toxic nature it has not been used widely as a flame retardant.
Toxicity and hazards
Fe(CO)5 is toxic, which is of concern because of its volatility (vapour pressure: 21 millimetres of mercury (2.8 kPa) at 20 °C). If inhaled, iron pentacarbonyl may cause lung irritation, toxic pneumonitis, or pulmonary edema. Like other metal carbonyls, Fe(CO)5 is flammable. It is, however, considerably less toxic than nickel tetracarbonyl.
In regards to occupational exposures to iron pentacarbonyl, the National Institute for Occupational Safety and Health has set a recommended exposure limit at 0.1 ppm (0.23 mg/m3) over an eight-hour time-weighted average, and a short-term exposure limit at 0.2 ppm (0.45 mg/m3).[12]
References
- 1 2 3 4 "NIOSH Pocket Guide to Chemical Hazards #0345". National Institute for Occupational Safety and Health (NIOSH).
- ↑ Samson, S.; Stephenson, G. R. (2004). "Pentacarbonyliron". In Paquette, L. Encyclopedia of Reagents for Organic Synthesis. New York, NY: J. Wiley & Sons. doi:10.1002/047084289.
- ↑ Mond, L.; Langer, C. (1891). "On iron carbonyls". J. Chem. Soc. Trans. 59: 1090–1093. doi:10.1039/CT8915901090.
- 1 2 Brauer, Georg (1963). Handbook of Preparative Inorganic Chemistry. 2 (2nd ed.). Newyork: Academic Press. p. 1743, 1751. ISBN 9780323161299.
- 1 2 Wildermuth, Egon; Stark, Hans; Friedrich, Gabriele; Ebenhöch, Franz Ludwig; Kühborth, Brigitte; Silver, Jack; Rituper, Rafael (2005), "Iron Compounds", Ullmann's Encyclopedia of Industrial Chemistry, Weinheim: Wiley-VCH, doi:10.1002/14356007.a14_591
- ↑ Therien, M. J.; Trogler, W. C. (1990). "Bis(phosphine) derivatives of iron pentacarbonyl and tetracarbonyl(tri-tert-butylphosphine)iron(0)". Inorg. Synth. 28: 173–9. doi:10.1002/9780470132593.ch45. ISBN 978-0-470-13259-3.
- ↑ Keiter, R. L.; Keiter, E. A.; Boecker, C. A.; Miller, D. R.; Hecker, K. H. (1997). "Tricarbonylbis(phosphine)iron(0) complexes". Inorg. Synth. 31: 210–214. doi:10.1002/9780470132623.ch31. ISBN 978-0-470-13262-3.
- ↑ Finke, R. G.; Sorrell, T. N. "Nucleophilic Acylation with Disodium Tetracarbonylferrate: Methyl 7-Oxoheptanoate and Methyl 7-oxooctonoate". Org. Synth.; Coll. Vol., 6, p. 807
- ↑ Pettit, R.; Henery, J. "Cyclobutadieneiron Tricarbonyl". Org. Synth.; Coll. Vol., 6, p. 310
- ↑ Birch, A. J.; Chamberlain, K. B. "Tricarbonyl[(2,3,4,5-η)-2,4-Cyclohexadien-1-one]iron and Tricarbonyl[(1,2,3,4,5-η)-2-Methoxy-2,4-Cyclohexadien-1-yl]Iron(1+) Hexafluorophosphate(1−) from Anisole". Org. Synth.; Coll. Vol., 6, p. 996
- ↑ Lask, G.; Wagner, H. Gg. (1962). "Influence of additives on the velocity of laminar flames". Eighth International Symposium on Combustion: 432–438.
- ↑ "Iron pentacarbonyl (as Fe)". NIOSH Pocket Guide to Chemical Hazards. Centers for Disease Control and Prevention. April 4, 2011. Retrieved November 19, 2013.