Normetanephrine

Normetanephrine
Names
IUPAC name
4-(2-amino-1-hydroxy-ethyl)- 2-methoxy-phenol
Identifiers
97-31-4 YesY
3D model (Jmol) Interactive image
ChEMBL ChEMBL774 YesY
ChemSpider 1200 YesY
6643
MeSH Normetanephrine
PubChem 1237
Properties
C9H13NO3
Molar mass 183.204 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
YesY verify (what is YesYN ?)
Infobox references

Normetanephrine is a metabolite of norepinephrine created by action of catechol-O-methyl transferase on norepinephrine. It is excreted in the urine and found in certain tissues. It is a marker for catecholamine-secreting tumors such as pheochromocytoma.

Norepinephrine degradation. Normetanephrine is shown at top left. Enzymes are shown in boxes.[1]

References

  1. Figure 11-4 in: Flower, R.; Rang, H. P.; Dale, M. M.; Ritter, J. M. (2007). Rang & Dale's Pharmacology. Edinburgh: Churchill Livingstone. ISBN 0-443-06911-5.


This article is issued from Wikipedia - version of the 6/4/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.