Nucleoporin 43

NUP43
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4I79, 5A9Q
Identifiers
Aliases	NUP43, bA350J20.1, p42, nucleoporin 43kDa, nucleoporin 43
External IDs	MGI: 1917162 HomoloGene: 11639 GeneCards: NUP43
Gene ontology Molecular function • protein binding Cellular component • condensed chromosome kinetochore • cytosol • nuclear envelope • nuclear pore • chromosome • nuclear pore outer ring • chromosome, centromeric region • nucleus • kinetochore Biological process • mRNA transport • mitotic nuclear division • viral transcription • chromosome segregation • protein sumoylation • cell division • mitotic nuclear envelope disassembly • transport • regulation of cellular response to heat • protein transport • cell cycle • gene silencing by RNA • viral process • regulation of glucose transport • intracellular transport of virus • mRNA export from nucleus • sister chromatid cohesion • tRNA export from nucleus Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	348995	69912
Ensembl	ENSG00000120253	ENSMUSG00000040034
UniProt	Q8NFH3	P59235
RefSeq (mRNA)	NM_024647 NM_198887	NM_145706
RefSeq (protein)	NP_942590.1	NP_663752.2
Location (UCSC)	Chr 6: 149.72 – 149.75 Mb	Chr 10: 7.67 – 7.68 Mb
PubMed search	[1]	[2]
Wikidata

View/Edit Human

View/Edit Mouse

Nucleoporin 43 (Nup43) is a protein that in humans is encoded by the NUP43 gene.^[3][4]

Bidirectional transport of macromolecules between the cytoplasm and nucleus occurs through nuclear pore complexes (NPCs) embedded in the nuclear envelope. NPCs are composed of subcomplexes, and NUP43 is part of one such subcomplex, Nup107-160 (Loiodice et al., 2004).[supplied by OMIM]^[4]

References

1. "Human PubMed Reference:".
2. "Mouse PubMed Reference:".
3. Cronshaw JM, Krutchinsky AN, Zhang W, Chait BT, Matunis MJ (Sep 2002). "Proteomic analysis of the mammalian nuclear pore complex". J Cell Biol. 158 (5): 915–27. doi:10.1083/jcb.200206106. PMC 2173148. PMID 12196509.
4. "Entrez Gene: NUP43 nucleoporin 43kDa".

Further reading

• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination.". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Loïodice I, Alves A, Rabut G, et al. (2005). "The entire Nup107-160 complex, including three new members, is targeted as one entity to kinetochores in mitosis.". Mol. Biol. Cell. 15 (7): 3333–44. doi:10.1091/mbc.E03-12-0878. PMC 452587. PMID 15146057.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline.". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006.". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.