OR10J5

OR10J5
Identifiers
Aliases	OR10J5, OR1-28, olfactory receptor family 10 subfamily J member 5
External IDs	MGI: 106648 HomoloGene: 7460 GeneCards: OR10J5
Gene ontology Molecular function • G-protein coupled receptor activity • olfactory receptor activity • signal transducer activity • neurotransmitter receptor activity • G-protein coupled serotonin receptor activity Cellular component • integral component of membrane • plasma membrane • membrane • dendrite • integral component of plasma membrane Biological process • G-protein coupled receptor signaling pathway • sensory perception of smell • detection of chemical stimulus involved in sensory perception of smell • signal transduction • response to stimulus • chemical synaptic transmission • adenylate cyclase-activating serotonin receptor signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	127385	18313
Ensembl	ENSG00000184155	ENSMUSG00000037924
UniProt	Q8NHC4	n/a
RefSeq (mRNA)	NM_001004469	NM_008763
RefSeq (protein)	NP_001004469.1	n/a
Location (UCSC)	Chr 1: 159.54 – 159.54 Mb	Chr 1: 172.96 – 172.96 Mb
PubMed search	[1]	[2]
Wikidata

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Olfactory receptor 10J5 is a protein that in humans is encoded by the OR10J5 gene.^[3]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.^[3]

References

1. "Human PubMed Reference:".
2. "Mouse PubMed Reference:".
3. "Entrez Gene: OR10J5 olfactory receptor, family 10, subfamily J, member 5".

Further reading

• Gilad Y, Bustamante CD, Lancet D, Pääbo S (2003). "Natural Selection on the Olfactory Receptor Gene Family in Humans and Chimpanzees". Am. J. Hum. Genet. 73 (3): 489–501. doi:10.1086/378132. PMC 1180675. PMID 12908129.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

• OR10J5 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.