OR2B6

OR2B6
Identifiers
Aliases	OR2B6, OR2B1, OR2B1P, OR2B5, OR2B6P, OR5-40, OR5-41, OR6-31, dJ408B20.2, olfactory receptor family 2 subfamily B member 6
External IDs	MGI: 104715 HomoloGene: 40838 GeneCards: OR2B6
Gene ontology Molecular function • G-protein coupled receptor activity • olfactory receptor activity • signal transducer activity Cellular component • integral component of membrane • plasma membrane • membrane Biological process • sensory perception of smell • G-protein coupled receptor signaling pathway • signal transduction • response to stimulus • detection of chemical stimulus involved in sensory perception of smell Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	26212	218066
Ensembl	ENSG00000124657	ENSMUSG00000036658
UniProt	P58173	Q60890
RefSeq (mRNA)	NM_012367	NM_146542
RefSeq (protein)	NP_036499.1	NP_666753.2
Location (UCSC)	Chr 6: 27.96 – 27.96 Mb	Chr 13: 21.64 – 21.64 Mb
PubMed search	[1]	[2]
Wikidata

View/Edit Human

View/Edit Mouse

Olfactory receptor 2B6 is a protein that in humans is encoded by the OR2B6 gene.^[3][4]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.^[4]

See also

• Olfactory receptor

References

1. "Human PubMed Reference:".
2. "Mouse PubMed Reference:".
3. Rouquier S, Taviaux S, Trask BJ, Brand-Arpon V, van den Engh G, Demaille J, Giorgi D (Mar 1998). "Distribution of olfactory receptor genes in the human genome". Nat Genet. 18 (3): 243–50. doi:10.1038/ng0398-243. PMID 9500546.
4. "Entrez Gene: OR2B6 olfactory receptor, family 2, subfamily B, member 6".

Further reading

• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6.". Nature. 425 (6960): 805–11. doi:10.1038/nature02055. PMID 14574404.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family.". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.

External links

• OR2B6 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.