OR4D1

OR4D1
Identifiers
Aliases	OR4D1, OR17-23, OR4D3, OR4D4P, TPCR16, olfactory receptor family 4 subfamily D member 1
External IDs	MGI: 3030298 HomoloGene: 44975 GeneCards: OR4D1
Gene ontology Molecular function • G-protein coupled receptor activity • transmembrane signaling receptor activity • signal transducer activity • olfactory receptor activity Cellular component • membrane • plasma membrane • integral component of membrane Biological process • detection of chemical stimulus involved in sensory perception • signal transduction • response to stimulus • detection of chemical stimulus involved in sensory perception of smell • G-protein coupled receptor signaling pathway • sensory perception of smell Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	26689	258407
Ensembl	ENSG00000141194	ENSMUSG00000060787
UniProt	Q15615	n/a
RefSeq (mRNA)	NM_012374	NM_146412
RefSeq (protein)	NP_036506.1	n/a
Location (UCSC)	Chr 17: 58.16 – 58.16 Mb	Chr 11: 87.91 – 87.92 Mb
PubMed search	[1]	[2]
Wikidata

View/Edit Human

View/Edit Mouse

Olfactory receptor 4D1 is a protein that in humans is encoded by the OR4D1 gene.^[3][4]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.^[4]

See also

• Olfactory receptor

References

1. "Human PubMed Reference:".
2. "Mouse PubMed Reference:".
3. Vanderhaeghen P, Schurmans S, Vassart G, Parmentier M (Apr 1997). "Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species". Genomics. 39 (3): 239–46. doi:10.1006/geno.1996.4490. PMID 9119360.
4. "Entrez Gene: OR4D1 olfactory receptor, family 4, subfamily D, member 1".

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes.". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family.". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

• OR4D1 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.