Oxiconazole

Oxiconazole
Clinical data

Trade names	Oxistat, Oxizole
AHFS/Drugs.com	Monograph
MedlinePlus	a689004
ATC code	D01AC11 (WHO) G01AF17 (WHO)
Identifiers
IUPAC name (E)-[1-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-yl)ethylidene][(2,4-dichlorophenyl)methoxy]amine
CAS Number	64211-46-7^Y
PubChem (CID)	5361463
DrugBank	DB00239^Y
ChemSpider	4514745^Y
UNII	RQ8UL4C17S^Y
KEGG	D00885^Y
ChEBI	CHEBI:7825^N
ChEMBL	CHEMBL1262^N
ECHA InfoCard	100.058.828
Chemical and physical data
Formula	C₁₈H₁₃Cl₄N₃O
Molar mass	429.126 g/mol
3D model (Jmol)	Interactive image
SMILES Clc3ccc(/C(=N\OCc1ccc(Cl)cc1Cl)Cn2ccnc2)c(Cl)c3
InChI InChI=1S/C18H13Cl4N3O/c19-13-2-1-12(16(21)7-13)10-26-24-18(9-25-6-5-23-11-25)15-4-3-14(20)8-17(15)22/h1-8,11H,9-10H2/b24-18-^Y Key:QRJJEGAJXVEBNE-MOHJPFBDSA-N^Y
^NY (what is this?) (verify)

Oxiconazole (trade names Oxistat in the US, Oxizole in Canada) is an antifungal medication typically administered in a cream or lotion to treat skin infections, such as athlete's foot, jock itch and ringworm. It can also be prescribed to treat the skin rash known as tinea versicolor, caused by systemic yeast overgrowth (Candida spp.).

References

Wall/
membrane

Ergosterol
inhibitors

Imidazoles	Topical: bifonazole^‡ butoconazole chlormidazole^‡ clotrimazole^# croconazole^‡ econazole fenticonazole^‡ flutrimazole isoconazole^‡ ketoconazole luliconazole miconazole^# neticonazole^‡ omoconazole^‡ oxiconazole sertaconazole sulconazole tioconazole Systemic: ketoconazole

Triazoles	Topical: efinaconazole fluconazole^# fosfluconazole terconazole Systemic: fluconazole^# hexaconazole^‡ isavuconazole itraconazole posaconazole voriconazole Unknown: albaconazole^‡ ravuconazole^†

Thiazoles	Topical: abafungin^‡

Allylamines	Topical: naftifine terbinafine Systemic: terbinafine

Benzylamines	Topical: butenafine

Others

Intracellular

Pyrimidine analogues/ thymidylate synthase inhibitors	flucytosine^#

Mitotic inhibitors	griseofulvin^#

Aminoacyl tRNA synthetase inhibitors	tavaborole

Others

Arsenic compounds

Quinoline derivatives

Imidazoles	Metronidazole Clotrimazole Miconazole Econazole Ornidazole Isoconazole Tioconazole Ketoconazole Fenticonazole Azanidazole Propenidazole Butoconazole Omoconazole Oxiconazole Flutrimazole

Triazoles	Terconazole

Polyenes	Nystatin Natamycin Amphotericin B

Other	Ciclopirox Methylrosaniline

Other

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