Alpha,alpha-trehalose-phosphate synthase (GDP-forming)
alpha,alpha-trehalose-phosphate synthase (GDP-forming) | |||||||||
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Identifiers | |||||||||
EC number | 2.4.1.36 | ||||||||
CAS number | 37257-32-2 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / EGO | ||||||||
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In enzymology, an alpha,alpha-trehalose-phosphate synthase (GDP-forming) (EC 2.4.1.36) is an enzyme that catalyzes the chemical reaction
- GDP-glucose + glucose 6-phosphate GDP + alpha,alpha-trehalose 6-phosphate
Thus, the two substrates of this enzyme are GDP-glucose and glucose 6-phosphate, whereas its two products are GDP and alpha,alpha'-trehalose 6-phosphate.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is GDP-glucose:D-glucose-6-phosphate 1-alpha-D-glucosyltransferase. Other names in common use include GDP-glucose-glucose-phosphate glucosyltransferase, guanosine diphosphoglucose-glucose phosphate glucosyltransferase, and trehalose phosphate synthase (GDP-forming).
References
- Elbein AD (1967). "Carbohydrate metabolism in Streptomyces hygroscopicus. I. Enzymatic synthesis of trehalose phosphate from guanosine diphosphate D-glucose-14C". J. Biol. Chem. 242 (3): 403–6. PMID 6022837.
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