A-1,4-glucan-protein synthase (UDP-forming)

Alpha-1,4-glucan-protein synthase (UDP-forming)
Identifiers
EC number 2.4.1.112
CAS number 152478-54-1
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Alpha-1,4-glucan-protein synthase (UDP-forming) (EC 2.4.1.112, UDP-glucose:protein glucosyltransferase, glycogen initiator synthase, UDPGlc:protein transglucosylase, UPTG, uridine diphosphoglucose protein transglucosylase I, proglycogen synthase, uridine diphosphoglucose-protein 4-alpha-glucosyltransferase, uridine diphosphoglucose-protein glucosyltransferase, UDP-glucose protein transglucosylase, UDP-glucose-protein glucosyltransferase, uridine diphosphate glucose-protein transglucosylase I) is an enzyme with systematic name UDP-glucose:protein 4-alpha-glucosyltransferase.[1][2][3] This enzyme catalyses the following chemical reaction

UDP-glucose + protein UDP + alpha-D-glucosyl-protein

The enzyme builds up alpha-1,4-glucan chains covalently bound to protein.

References

  1. Barengo, R.; Krisman, C.R. (1978). "Initiation of glycogen biosynthesis in Escherichia coli. Studies of the properties of the enzymes involved". Biochim. Biophys. Acta. 540 (2): 190–196. doi:10.1016/0304-4165(78)90131-9. PMID 418819.
  2. Butler, N.A.; Lee, E.Y.C.; Whelan, W.J. (1977). "A protein-bound glycogen component of rat liver". Carbohydr. Res. 55: 73–82. doi:10.1016/s0008-6215(00)84444-4. PMID 861979.
  3. Krisman, C.R.; Barengo, R. (1975). "A precursor of glycogen biosynthesis: α-1,4-glucan-protein". Eur. J. Biochem. 52: 117–123. doi:10.1111/j.1432-1033.1975.tb03979.x. PMID 809265.

External links

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