Diglucosyl diacylglycerol synthase
| diglucosyl diacylglycerol synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.4.1.208 | ||||||||
| CAS number | 168680-19-1 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / EGO | ||||||||
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In enzymology, a diglucosyl diacylglycerol synthase (EC 2.4.1.208) is an enzyme that catalyzes the chemical reaction
- UDP-glucose + 1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol 1,2-diacyl-3-O-(alpha-D-glucopyranosyl(1->2)-O-alpha-D- glucopyranosyl)sn-glycerol + UDP
Thus, the two substrates of this enzyme are UDP-glucose and 1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol, whereas its 2 products are 1,2-diacyl-3-O-(alpha-D-glucopyranosyl(1-2)-O-alpha-D-glucopyranosyl)sn-glycerol, and UDP.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol (1->2) glucosyltransferase. Other names in common use include monoglucosyl diacylglycerol (1->2) glucosyltransferase, MGlcDAG (1->2) glucosyltransferase, and DGlcDAG synthase. It employs one cofactor, magnesium.
References
- Karlsson OP, Rytomaa M, Dahlqvist A, Kinnunen PK, Wieslander A (1996). "Correlation between bilayer lipid dynamics and activity of the diglucosyldiacylglycerol synthase from Acholeplasma laidlawii membranes". Biochemistry. 35 (31): 10094–102. doi:10.1021/bi9602876. PMID 8756472.