Galactolipid galactosyltransferase
| galactolipid galactosyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.4.1.184 | ||||||||
| CAS number | 66676-74-2 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / EGO | ||||||||
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In enzymology, a galactolipid galactosyltransferase (EC 2.4.1.184) is an enzyme that catalyzes the chemical reaction
- 2 3-(beta-D-galactosyl)-1,2-diacyl-sn-glycerol 3-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-1,2-diacyl-sn- glycerol + 1,2-diacyl-sn-glycerol
Hence, this enzyme has one substrate, 3-(beta-D-galactosyl)-1,2-diacyl-sn-glycerol, but 3 products: [[3-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-1,2-diacyl-sn-]], glycerol, and 1,2-diacyl-sn-glycerol.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is 3-(beta-D-galactosyl)-1,2-diacyl-sn-glycerol:mono-3-(beta-D-galactos yl)-1,2-diacyl-sn-glycerol beta-D-galactosyltransferase. Other names in common use include galactolipid-galactolipid galactosyltransferase, galactolipid:galactolipid galactosyltransferase, interlipid galactosyltransferase, GGGT, DGDG synthase (ambiguous), and digalactosyldiacylglycerol synthase (ambiguous). This enzyme participates in glycerolipid metabolism.
References
- Dorne AJ, Block MA, Joyard J, Douce R (1982). "The galactolipid-galactolipid galactosyltransferase is located on the outer surface of the outer-membrane of the chloroplast envelope". FEBS Lett. 145: 30–34. doi:10.1016/0014-5793(82)81200-3.
- Dorne AJ, Douce R (1986). "Localization of galactolipid:galactolipid galactosyltransferase and acyltransferase in outer envelope membrane of spinach chloroplasts". Biochim. Biophys. Acta. 877: 281–289. doi:10.1016/0005-2760(86)90305-x.
- Heemskerk JWM; Jacobs FHH; Wintermans JFGM (1988). "UDPgalactose-independent synthesis of monogalactosyldiacylglycerol An enzymatic activity of the spinach chloroplast envelope". Biochim. Biophys. Acta. 961: 38–47. doi:10.1016/0005-2760(88)90128-2.
- Kelly AA, Froehlich JE, Dormann P (2003). "Disruption of the two digalactosyldiacylglycerol synthase genes DGD1 and DGD2 in Arabidopsis reveals the existence of an additional enzyme of galactolipid synthesis". Plant. Cell. 15 (11): 2694–706. doi:10.1105/tpc.016675. PMC 280572
. PMID 14600212. - Benning C, Ohta H (2005). "Three enzyme systems for galactoglycerolipid biosynthesis are coordinately regulated in plants". J. Biol. Chem. 280 (4): 2397–400. doi:10.1074/jbc.R400032200. PMID 15590685.