Glucosyl-3-phosphoglycerate synthase
| Glucosyl-3-phosphoglycerate synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.4.1.266 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Glucosyl-3-phosphoglycerate synthase (EC 2.4.1.266, GpgS protein, GPG synthase, glucosylphosphoglycerate synthase) is an enzyme with systematic name NDP-glucose:3-phospho-D-glycerate 2-alpha-D-glucosyltransferase.[1][2][3][4][5][6] This enzyme catalyses the following chemical reaction
- NDP-glucose + 3-phospho-D-glycerate NDP + 2-O-(alpha-D-glucopyranosyl)-3-phospho-D-glycerate
The enzyme is involved in biosynthesis of 2-O-(alpha-D-glucopyranosyl)-D-glycerate.
References
- ↑ Costa, J.; Empadinhas, N.; da Costa, M.S. (2007). "Glucosylglycerate biosynthesis in the deepest lineage of the bacteria: characterization of the thermophilic proteins GpgS and GpgP from Persephonella marina". J. Bacteriol. 189 (5): 1648–1654. doi:10.1128/JB.00841-06. PMC 1855766
. PMID 17189358. - ↑ Costa, J.; Empadinhas, N.; Goncalves, L.; Lamosa, P.; Santos, H.; da Costa, M.S. (2006). "Characterization of the biosynthetic pathway of glucosylglycerate in the archaeon Methanococcoides burtonii". J. Bacteriol. 188 (3): 1022–1030. doi:10.1128/JB.188.3.1022-1030.2006. PMC 1347341. PMID 16428406.
- ↑ Empadinhas, N.; Albuquerque, L.; Mendes, V.; Macedo-Ribeiro, S.; da Costa, M.S. (2008). "Identification of the mycobacterial glucosyl-3-phosphoglycerate synthase". FEMS Microbiol. Lett. 280 (2): 195–202. doi:10.1111/j.1574-6968.2007.01064.x. PMID 18221489.
- ↑ Pereira, P.J.; Empadinhas, N.; Albuquerque, L.; Sa-Moura, B.; da Costa, M.S.; Macedo-Ribeiro, S. (2008). Song, Haiwei, ed. "Mycobacterium tuberculosis glucosyl-3-phosphoglycerate synthase: structure of a key enzyme in methylglucose lipopolysaccharide biosynthesis". PLoS ONE. 3 (11): #e3748–e3748. Bibcode:2008PLoSO...3.3748P. doi:10.1371/journal.pone.0003748. PMC 2581804. PMID 19015727.
- ↑ Gest, P.; Kaur, D.; Pham, H.T.; van der Woerd, M.; Hansen, E.; Brennan, P.J.; Jackson, M.; Guerin, M.E. (2008). "Preliminary crystallographic analysis of GpgS, a key glucosyltransferase involved in methylglucose lipopolysaccharide biosynthesis in Mycobacterium tuberculosis". Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 64 (Pt 12): 1121–1124. doi:10.1107/S1744309108032892. PMC 2593697. PMID 19052364.
- ↑ Kaur, D.; Pham, H.; Larrouy-Maumus, G.; Riviere, M.; Vissa, V.; Guerin, M.E.; Puzo, G.; Brennan, P.J.; Jackson, M. (2009). Herman, Christophe, ed. "Initiation of methylglucose lipopolysaccharide biosynthesis in mycobacteria". PLoS ONE. 4 (5): #e544–e5447. Bibcode:2009PLoSO...4.5447K. doi:10.1371/journal.pone.0005447. PMC 2674218. PMID 19421329.
External links
- Glucosyl-3-phosphoglycerate synthase at the US National Library of Medicine Medical Subject Headings (MeSH)
This article is issued from Wikipedia - version of the 5/19/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.