Inositol 3-alpha-galactosyltransferase
inositol 3-alpha-galactosyltransferase | |||||||||
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Identifiers | |||||||||
EC number | 2.4.1.123 | ||||||||
CAS number | 79955-89-8 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / EGO | ||||||||
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In enzymology, an inositol 3-alpha-galactosyltransferase (EC 2.4.1.123) is an enzyme that catalyzes the chemical reaction
- UDP-galactose + myo-inositol UDP + O-alpha-D-galactosyl-(1->3)-1D-myo-inositol
Thus, the two substrates of this enzyme are UDP-galactose and myo-inositol, whereas its two products are UDP and [[O-alpha-D-galactosyl-(1->3)-1D-myo-inositol]].
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-galactose:myo-inositol 3-alpha-D-galactosyltransferase. Other names in common use include UDP-D-galactose:inositol galactosyltransferase, UDP-galactose:myo-inositol 1-alpha-D-galactosyltransferase, UDPgalactose:myo-inositol 1-alpha-D-galactosyltransferase, galactinol synthase, inositol 1-alpha-galactosyltransferase, and uridine diphosphogalactose-inositol galactosyltransferase. This enzyme participates in galactose metabolism.
References
- Pharr DM, Sox, HN, Locy RD, Huber SC (1981). "Partial characterization of the galactinol forming enzyme from leaves of Cucumis sativus L". Plant Sci. Lett. 23: 25–33. doi:10.1016/0304-4211(81)90021-3.