Mannosylglycerate synthase

Mannosylglycerate synthase
Identifiers
EC number 2.4.1.269
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Mannosylglycerate synthase (EC 2.4.1.269) is an enzyme with systematic name GDP-mannose:D-glycerate 2-alpha-D-mannosyltransferase.[1][2] This enzyme catalyses the following chemical reaction

GDP-mannose + D-glycerate GDP + 2-O-(alpha-D-mannopyranosyl)-D-glycerate

Depending on conditions mannosylglycerate synthase is more or less specific for the GDP-mannose and D-glycerate.

See also

References

  1. Martins, L.O.; Empadinhas, N.; Marugg, J.D.; Miguel, C.; Ferreira, C.; da Costa, M.S.; Santos, H. (1999). "Biosynthesis of mannosylglycerate in the thermophilic bacterium Rhodothermus marinus. Biochemical and genetic characterization of a mannosylglycerate synthase". J. Biol. Chem. 274 (50): 35407–35414. doi:10.1074/jbc.274.50.35407. PMID 10585410.
  2. Flint, J.; Taylor, E.; Yang, M.; Bolam, D.N.; Tailford, L.E.; Martinez-Fleites, C.; Dodson, E.J.; Davis, B.G.; Gilbert, H.J.; Davies, G.J. (2005). "Structural dissection and high-throughput screening of mannosylglycerate synthase". Nat. Struct. Mol. Biol. 12 (7): 608–614. doi:10.1038/nsmb950. PMID 15951819.
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