POLD2

POLD2
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
Aliases POLD2
External IDs MGI: 1097163 HomoloGene: 4538 GeneCards: POLD2
RNA expression pattern
More reference expression data
Orthologs
Species Human Mouse
Entrez

5425

18972

Ensembl

ENSG00000106628

ENSMUSG00000020471

UniProt

P49005

O35654

RefSeq (mRNA)

NM_001127218
NM_001256879
NM_006230

NM_008894

RefSeq (protein)

NP_001120690.1
NP_001243808.1
NP_006221.2

NP_032920.2

Location (UCSC) Chr 7: 44.11 – 44.12 Mb Chr 11: 5.87 – 5.88 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

DNA polymerase delta subunit 2 is an enzyme that in humans is encoded by the POLD2 gene.[3][4] It is a component of the DNA polymerase delta complex.

Interactions

POLD2 has been shown to interact with PCNA.[5]

References

  1. "Human PubMed Reference:".
  2. "Mouse PubMed Reference:".
  3. Zhang J, Tan CK, McMullen B, Downey KM, So AG (Feb 1996). "Cloning of the cDNAs for the small subunits of bovine and human DNA polymerase delta and chromosomal location of the human gene (POLD2)". Genomics. 29 (1): 179–86. doi:10.1006/geno.1995.1229. PMID 8530069.
  4. "Entrez Gene: POLD2 polymerase (DNA directed), delta 2, regulatory subunit 50kDa".
  5. Lu, Xiaoqing; Tan Cheng-Keat; Zhou Jin-Qiu; You Min; Carastro L Michael; Downey Kathleen M; So Antero G (Jul 2002). "Direct interaction of proliferating cell nuclear antigen with the small subunit of DNA polymerase delta". J. Biol. Chem. United States. 277 (27): 24340–5. doi:10.1074/jbc.M200065200. ISSN 0021-9258. PMID 11986310.

Further reading


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