Sodium aurothiosulfate
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| Clinical data | |
|---|---|
| Routes of administration | Intramuscular injection |
| ATC code | M01CB02 (WHO) |
| Identifiers | |
| |
| CAS Number |
18497-75-1  |
| PubChem (CID) | 170028 |
| Chemical and physical data | |
| Formula | AuNa3O6S4 |
| Molar mass | 332.08452 g/mol |
| (verify) | |
Sodium aurothiosulfate is the inorganic compound with the formula Na3Au(S2O3)2·2H2O. This salt contains an anionic linear coordination complex of gold(I) bound to two thiosulfate ligands.[1][2] Like several other gold compounds, this species is used as an antirheumatic.[3]The first placebo-controlled trial was probably conducted in 1931, when sanocrysin was compared with distilled water for the treatment of tuberculosis.[4]
References
- ↑ Baggio, R (1973). "Crystal and molecular structure of trisodium dithiosulphate aurate(I), dihydrate, Na3[Au(S2O3)2],2H2O". Journal of Inorganic and Nuclear Chemistry. 35 (9): 3191. doi:10.1016/0022-1902(73)80019-3.
- ↑ Tobön-Zapata, G (1997). "Vibrational spectrum of Sanocrysin". Spectrochimica Acta Part a Molecular and Biomolecular Spectroscopy. 53 (2): 183. doi:10.1016/S1386-1425(97)83024-7.
- ↑ Shaw, III, C. F. (1999). "Gold-Based Therapeutic Agents". Chemical Reviews. 99 (9): 2589–600. doi:10.1021/cr980431o. PMID 11749494.
- ↑ Ethical and regulatory aspects of clinical research: readings and commentary, Ezekiel J. Emanuel, Johns Hopkins University Press, 2003, p 140
Source of Chemical Formula: http://medical.merriam-webster.com/medical/gold%20sodium%20thiomalate
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