Sphingosine beta-galactosyltransferase

sphingosine beta-galactosyltransferase
Identifiers
EC number 2.4.1.23
CAS number 9032-90-0
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a sphingosine beta-galactosyltransferase (EC 2.4.1.23) is an enzyme that catalyzes the chemical reaction[1]

UDP-galactose + sphingosine UDP + psychosine

Thus, the two substrates of this enzyme are UDP-galactose and sphingosine, whereas its two products are UDP and psychosine.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-galactose:sphingosine 1-beta-galactosyltransferase. Other names in common use include psychosine-UDP galactosyltransferase, galactosyl-sphingosine transferase, psychosine-uridine diphosphate galactosyltransferase, UDP-galactose:sphingosine O-galactosyl transferase, uridine diphosphogalactose-sphingosine beta-galactosyltransferase, and UDP-galactose:sphingosine 1-beta-galactotransferase. This enzyme participates in sphingolipid metabolism.

References

  1. Cleland, W.W.; Kennedy, E.P. (1960). "The enzymatic synthesis of psychosine". J. Biol. Chem. 235: 45–51. PMID 13810623.


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