Bisphenol AF

Bisphenol AF

Names
IUPAC name 4-[1,1,1,3,3,3-Hexafluoro-2-(4-hydroxyphenyl)propan-2-yl]phenol
Other names Biphenol AF; Hexafluorobisphenol A; Hexafluorodiphenylolpropane; Bisphenol A hexafluoride; 4,4'-(Hexafluoroisopropylidene)diphenol; Hexafluoroacetone bisphenol A; 2,2-Bis(4-hydroxyphenyl)hexafluoropropane
Identifiers
CAS Number	1478-61-1
3D model (Jmol)	Interactive image
Abbreviations	BPAF
ChemSpider	66498
ECHA InfoCard	100.014.579
PubChem	73864
InChI InChI=1S/C15H10F6O2/c16-14(17,18)13(15(19,20)21,9-1-5-11(22)6-2-9)10-3-7-12(23)8-4-10/h1-8,22-23H Key: ZFVMWEVVKGLCIJ-UHFFFAOYSA-N InChI=1/C15H10F6O2/c16-14(17,18)13(15(19,20)21,9-1-5-11(22)6-2-9)10-3-7-12(23)8-4-10/h1-8,22-23H Key: ZFVMWEVVKGLCIJ-UHFFFAOYAS
SMILES C1=CC(=CC=C1C(C2=CC=C(C=C2)O)(C(F)(F)F)C(F)(F)F)O
Properties
Chemical formula	C15H10F6O2
Molar mass	336.23 g·mol^−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Bisphenol AF (BPAF) is a fluorinated organic compound related to bisphenol A in which the two methyl groups are replaced with trifluoromethyl groups.

Whereas BPA binds with human estrogen-related receptor gamma (ERR-γ), BPAF all but ignores ERR-γ. Instead, BPAF activates ERR-α and binds to and disables ERR-β.^[1]

See also

• Bisphenol A
• Bisphenol S

References

1. Janet Raloff: Another plastics ingredient raises safety concerns, Science News, June 5th, 2010; Vol.177 #12 (p. 14)