GABRR3

GABRR3
Identifiers
Aliases GABRR3
External IDs MGI: 3588203 HomoloGene: 26716 GeneCards: GABRR3
Targeted by Drug
isoguvacine, muscimol, gaboxadol, isonipecotic acid, picrotoxin[1]
Orthologs
Species Human Mouse
Entrez

200959

328699

Ensembl

ENSG00000183185

ENSMUSG00000074991

UniProt

A8MPY1

n/a

RefSeq (mRNA)

NM_001105580

NM_001081190

RefSeq (protein)

NP_001099050.1

n/a

Location (UCSC) Chr 3: 97.99 – 98.04 Mb Chr 16: 59.41 – 59.46 Mb
PubMed search [2] [3]
Wikidata
View/Edit HumanView/Edit Mouse

Gamma-aminobutyric acid receptor subunit rho-3 is a protein that in humans is encoded by the GABRR3 gene.[4] The protein encoded by this gene is a subunit of the GABAA-ρ receptor.

References

  1. ↑ "Drugs that physically interact with Gamma-aminobutyric acid receptor subunit rho-3 view/edit references on wikidata".
  2. ↑ "Human PubMed Reference:".
  3. ↑ "Mouse PubMed Reference:".
  4. ↑ Bailey ME, Albrecht BE, Johnson KJ, Darlison MG (October 1999). "Genetic linkage and radiation hybrid mapping of the three human GABA(C) receptor rho subunit genes: GABRR1, GABRR2 and GABRR3". Biochim. Biophys. Acta. 1447 (2–3): 307–12. doi:10.1016/S0167-4781(99)00167-0. PMID 10542332.

Further reading

  • Croci C, Brändstatter JH, Enz R (2003). "ZIP3, a new splice variant of the PKC-zeta-interacting protein family, binds to GABAC receptors, PKC-zeta, and Kv beta 2". J. Biol. Chem. 278 (8): 6128–35. doi:10.1074/jbc.M205162200. PMID 12431995. 
  • Craddock N, Jones L, Jones IR, et al. (2010). "Strong genetic evidence for a selective influence of GABAA receptors on a component of the bipolar disorder phenotype". Mol. Psychiatry. 15 (2): 146–53. doi:10.1038/mp.2008.66. PMID 19078961. 
  • Alakuijala A, Palgi M, Wegelius K, et al. (2005). "GABA receptor rho subunit expression in the developing rat brain". Brain Res. Dev. Brain Res. 154 (1): 15–23. doi:10.1016/j.devbrainres.2004.09.010. PMID 15617751. 
  • Bailey ME, Albrecht BE, Johnson KJ, Darlison MG (1999). "Genetic linkage and radiation hybrid mapping of the three human GABA(C) receptor rho subunit genes: GABRR1, GABRR2 and GABRR3". Biochim. Biophys. Acta. 1447 (2–3): 307–12. doi:10.1016/S0167-4781(99)00167-0. PMID 10542332. 
  • Gratacòs M, Costas J, de Cid R, et al. (2009). "Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment". Am. J. Med. Genet. B Neuropsychiatr. Genet. 150B (6): 808–16. doi:10.1002/ajmg.b.30902. PMID 19086053. 
  • Muzny DM, Scherer SE, Kaul R, et al. (2006). "The DNA sequence, annotation and analysis of human chromosome 3". Nature. 440 (7088): 1194–8. doi:10.1038/nature04728. PMID 16641997. 

External links


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