Dolichyl-phosphate-mannose—glycolipid alpha-mannosyltransferase
| dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.4.1.130 | ||||||||
| CAS number | 77967-76-1 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / EGO | ||||||||
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In enzymology, a dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase (EC 2.4.1.130) is an enzyme that catalyzes the chemical reaction in which an alpha-D-mannosyl residue is transferred from a dolichyl-phosphate D-mannose molecule into a membrane lipid-linked oligosaccharide.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is dolichyl-phosphate-D-mannose:glycolipid alpha-D-mannosyltransferase. Other names in common use include dolichol phosphomannose-oligosaccharide-lipid mannosyltransferase, and oligomannosylsynthase. This enzyme participates in n-glycan biosynthesis and glycan structures - biosynthesis 1.
References
- Rearick JI, Fujimoto K, Kornfeld S (1981). "Identification of the mannosyl donors involved in the synthesis of lipid-linked oligosaccharides". J. Biol. Chem. 256 (8): 3762–9. PMID 6163773.
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