International Classification of Diseases for Oncology

The International Classification of Diseases for Oncology (ICD-O) is a domain-specific extension of the International Statistical Classification of Diseases and Related Health Problems for tumor diseases. This classification is widely used by cancer registries.

It is currently in its third revision (ICD-O-3). ICD-10 includes a list of morphology codes. They stem from ICD-O second edition (ICD-O-2) that was valid at the time of publication.

Axes

The classification has two axes: topography and morphology.

Morphology

The morphology axis is for the shape and structure of the tumor.

This axis has particular importance because the Systematized Nomenclature of Medicine ("SNOMED") has adopted the ICD-O classification of morphology. SNOMED has been changing continuously, and several different versions of SNOMED are in use. Accordingly, mapping of ICD-O codes to SNOMED requires careful assessment of whether entities are indeed true matches.

Topography

The topography axis is for of the tumor's site in the body. It is standardized with the C section of ICD-10.

There were no changes in the topography axis between ICD-O-2 and ICD-O-3.

See List of ICD-10 codes#(C00–C97) Malignant Neoplasms for examples.

International Classification of Diseases for Oncology, Third Edition (ICD-O-3)

5th Digit Behaviour Code for Neoplasms

Morphology Codes (ICD-O-3) [1]

800 Neoplasms, NOS

M8000/0 Neoplasm, benign

M8000/1 Neoplasm, uncertain whether benign or malignant

M8000/3 Neoplasm, malignant

M8000/6 Neoplasm, metastatic

M8000/9 Neoplasm, malignant, uncertain whether primary or metastatic

M8001/0 Tumor cells, benign

M8001/1 Tumor cells, uncertain whether benign or malignant

M8001/3 Tumor cells, malignant

M8002/3 Malignant tumor, small cell type

M8003/3 Malignant tumor, giant cell type

M8004/3 Malignant tumor, spindle cell type

M8005/0 Clear cell tumor, NOS

M8005/3 Malignant tumor, clear cell type

801–804 Epithelial Neoplasms, NOS

805-808 Squamous Cell Neoplasms

809-811 Basal cell Neoplasms

812-813 Transitional cell Papillomas And Carcinomas

814–838 Adenomas And Adenocarcinomas

839–842 Adnexal And Skin appendage Neoplasms

M8390/0 Skin appendage adenoma (C44._)

M8390/3 Skin appendage carcinoma (C44._)

M8391/0 Follicular fibroma (C44._)

M8392/0 Syringofibroadenoma (C44._)

M8400/0 Sweat gland adenoma (C44._)

M8400/1 Sweat gland tumor, NOS (C44._)

M8400/3 Sweat gland adenocarcinoma (C44._)

M8401/0 Apocrine adenoma

M8401/3 Apocrine adenocarcinoma

M8402/0 Nodular hidradenoma (C44._)

M8402/3 Nodular hidradenoma, malignant (C44._)

M8403/0 Eccrine spiradenoma (C44._)

M8403/3 Malignant eccrine spiradenoma (C44._) M8404/0 Hidrocystoma (C44._)

M8405/0 Papillary hidradenoma

M8406/0 Papillary syringadenoma (C44._)

M8407/0 Syringoma, NOS (C44._)

M8407/3 Sclerosing sweat duct carcinoma (C44._)

M8408/0 Eccrine papillary adenoma (C44._)

M8408/1 Aggressive digital papillary adenoma (C44._)

M8408/3 Eccrine papillary adenocarcinoma (C44._)

M8409/0 Eccrine poroma (C44._)

M8410/0 Sebaceous adnoma (C44._)

M8410/3 Sebaceous adenocarcinoma (C44._)

M8413/3 Eccrine adenocarcinoma (C44._)

M8420/0 Ceruminous adenoma (C44.2)

M8420/3 Ceruminous adenocarcinioma (C44.2)

843 Mucoepidermoid Neoplasms

M8430/1 Mucoepidermoid tumor

M8430/3 Mucoepidermoid carcinoma

844–849 Cystic, Mucinous And Serous Neoplasms

M8440/0 Cystadenoma, NOS

M8440/3 Cystadenocarcinoma, NOS

M8441/0 Serous cystadenoma, NOS

M8441/3 Serous cystadenocarcinoma, NOS (C56.9)

M8442/1 Serous cystadenoma, borderline malignancy (C56.9)

M8443/0 Clear cell cystadenoma (C56.9)

M8444/1 Clear cell cystic tumor of borderline malignancy (C56.9)

M8450/0 Papillary cystadenoma, NOS (C56.9)

M8450/3 Papillary cystadenocarcinoma, NOS (C56.9)

M8451/1 Papillary cystadenoma, borderline malignancy (C56.9)

M8452/1 Solid pseudo papillary tumor (C25._)

M8452/3 Solid pseudopapillary carcinoma (C25._)

M8453/0 Intraductal papillary-mucinous adenoma (C25._)

M8453/1 Intraductal papillary-mucinous tumor with moderate dysplasia (C25._)

M8453/2 Intraductal papillary-mucinous carcinoma, non-invasive (C25._)

M8453/3 Intraductal papillary-mucinous carcinoma invasive (C25._)

M8454/0 Cystic tumor of atrio-ventricular node (C38.0)

M8460/0 Papillary serous cystadenoma, NOS (C56.9)

M8460/3 Papillary serous cystadenocarcinoma (C56.9)

M8461/0 Serous surface papilloma (C56.9)

M8461/3 Serous surface papillary carcinoma (C56.9)

M8462/1 Serous papillary cystic tumor of borderline malignancy (C56.9)

M8463/1 Serous surface papillary tumor of borderline malignancy (C56.9)

M8470/0 Mucinous cystadenoma, NOS (C56.9)

m8470/1 Mucinous cystic tumor with moderate dysplasia (C25._)

M8470/2 Mucinous cystadenocarcinoma, non-invasive (C25._)

M8470/3 Mucinous cystadenocarcinoma/ NOS (C56.9)

M8471/0 Papillary mucinous cystadenoma, NOS (C56.9)

M8471/3 papillary mucinous cystadenocarcinoma (C56.9)

M8472/1 Mucinous cystic tumor of borderline malignancy (C56.9)

M8473/1 Papillary mucinous cystadenoma, borderline malignancy (C56.9)

M8480/0 Mucinous adenoma

M8480/3 Mucinous adenocarcinoma

M8480/6 Pseudomyxoma peritonei

M8481/3 Mucin-producing adenocarcinoma

M8482/3 Mucinous adenocarcinoma, endocervical type

M8490/3 Signet ring cell carcinoma

M8490/6 Metastatic signet ring cell carcinoma

850–854 Ductal, Lobular And Medullary Neoplasms

M8500/2 Intraductal carcinoma, noninfiltrating, NOS

M8500/3 Infiltrating duct carcinoma, NOS (C50._)

M8501/2 Comedocarcinoma, noninfiltrating (C50._)

M8501/3 Comedocarcinoma, NOS (C50._)

M8502/3 Secretory carcinoma of breast (C50._)

M8503/0 Intraductal papilloma

M8503/2 Noninfiltrating intraductal papillary adenocarcinoma (C50._)

M8503/3 Intraductal papillary adenocarcinoma with invasion (C50._)

M8504/0 Intracystic papillary adenoma

M8504/2 Noninfiltrating intracystic carcinoma

M8504/3 Intracystic carcinoma, NOS

M8505/0 Intraductal papillomatosis, NOS

M8506/0 Adenoma of nipple (C50._)

M8507/2 Intraductal micropapillary carcinoma (C50._)

M8508/3 Cystic hypersecretory carcinoma (C50._)

M8510/3 Medullary carcinoma, NOS

M8512/3 Medullary carcinoma with lymphoid stroma

M8513/3 Atypical medullary carcinoma (C50._)

M8514/3 Duct carcinoma, desmoplastic type

M8520/2 Lobular carcinoma in situ, NOS (C50._)

M8520/3 Lobular carcinoma, NOS (C50._)

M8521/3 Infiltrating ductular carcinoma (C50._)

M8522/2 Intraductal carcinoma and lobular carcinoma in situ (C50._)

M8522/3 Infiltrating duct and lobular carcinoma (C50._)

M8523/3 Infiltrating duct mixed with other types of carcinoma (C50._)

M8524/3 Infiltrating lobular mixed with other types of carcinoma (C50._)

M8525/3 Polymorphous low grade adenocarcinoma

M8530/3 Inflammatory carcinoma (C50._)

M8540/3 Paget disease, mammary (C50._)

M8541/3 Paget disease and infiltrating duct carcinoma of breast (C50._)

M8542/3 Paget disease, extramammary (except paget disease of bone)

M8543/3 Paget disease and intraductal carcinoma of breast (C50._)

8550 Acinar cell neoplasms

M8550/0 Acinar cell adenoma

M8550/1 Acinar cell tumor

M8550/3 Acinar cell carcinoma

M8551/3 Acinar cell cystadenocarcinoma

856–857 Complex epithelial neoplasms

M8560/0 Mixed squamous cell and glandular papilloma

M8560/3 Adenosquamous carcinoma

M8561/0 Adenolymphoma (C07._, C08._)

M8562/3 Epithelial-myoepithelial carcinoma

M8570/3 Adenocarcinoma with squamous metaplasia

M8571/3 Adenocarcinoma with cartilaginous and osseus metaplasia

M8572/3 Adenocarcinoma with spindle cell metaplasia

M8573/3 Adenocarcinoma with apocrine metaplasia

M8574/3 Adenocarcinoma with neuroendocrine differentiation

M8575/3 Metaplastic carcinoma, NOS

M8576/3 Hepatoid adenocarcinoma

858 Thymic Epithelial Neoplasms

M8581/3 Thymoma, type A, malignant (C37.9)

M8582/1 Thymoma, type AB, NOS (C37.9)

M8582/3 thymoma, type AB, malignant (C37.9)

M8583/1 Thymoma, type B1, NOS (C37.9)

M8583/3 Thymoma, type B1, malignant (C37.9)

M8584/1 Thymoma, type B2, NOS (C37.9)

M8584/3 Thymoma, type B2, malignant (C37.9)

M8585/1 Thymoma, type B3, NOS (C37.9)

m8585/3 Thymoma, type B3, malignant (C37.9)

M8586/3 Thymic carcinoma, NOS (C37.9)

M8587/0 Ectopic hamartomatous thymoma

M8588/3 Spindle epithelial tumor with thymus-like element

M8589/3 Carcinoma showing thymus-like element

859–867 Specialized gonadal neoplasms

M8590/1 Sex cord-stromal tumor, NOS

M8591/1 Sex cord-gonadal stromal tumor, incompletely differentiated

M8592/1 Sex cord-gonadal stromal tumor, mixed forms

M8593/1 Stromal tumor with minor sex cord elements

M8600/0 Thecoma, NOS

M8600/3 Thecoma, malignant

M8601/0 Thecoma, luteinized

M8602/0 Sclerosing stromal tumor

M8610/0 Luteoma, NOS

M8620/1) Granulosa cell tumor, NOS

M8620/3 Granulosa cell tumor, malignant

M8621/1 Granulosa cell-theca cell tumor

M8622/1 Granulosa cell tumor, juvenile

M8623/1 Sex cord tumor with annular tubules

M8630/1 Androblastoma/Arrhenoblastoma, benign

M8630/1 Androblastoma/Arrhenoblastoma, NOS

M8630/3 Androblastoma/Arrhenoblastoma, malignant

M8631/0 Sertoli-Leydig cell tumor, well differentiated

M8631/1 Sertoli-Leydig cell tumor of intermediate differentiation

M8631/3 Sertoli-Leydig cell tumor, poorly differentiated

M8632/1 Gynandroblastoma

M8633/1 Sertoli-Leydig cell tumor, retiform

M8634/1 Sertoli-Leydig cell tumor, intermediate differentiation, with heterologous elements

M8634/3 Sertoli-Leydig cell tumor, poorly differentiated, with heterologous elements

M8640/1 Sertoli tumor, NOS

M8640/3 Sertoli cell carcinoma (C62._)

M8641/0 Sertoli cell tumor with lipid storage

M8642/1 large cell calcifying Sertoli cell tumor

M8650/0 Leydig cell tumor, bening (C62._)

M8650/3 Leydig cell tumor, malignant

M8660/0 Hilus cell tumor (C56.9)

M8670/0 Lipid cell tumor of ovary (C56.9)

M8670/3 Steroid cell tumor, malignant

M8641/0 Adrenal rest tumor

868–871 Paragangliomas And Glomus tumors

M8680/0 Paraganglioma, benign

M8680/1 Paraganglioma, NOS

M8680/3 paraganglioma, malignant

M8681/1 Sympathetic paraganglioma

M8682/1 Parasympathetic paraganglioma

M8683/0 Gangliocytic paraganglioma (C17.0)

M8690/1 Glomus jugulare tumor, NOS (C75.5)

M8691/1 Aortic body tumor (C75.5)

M8692/1 Carotid body tumor/paraganglioma (C75.4)

M8693/1 Extra-adrenal paraganglioma, NOS

M8693/3 Extra-adrenal paraganglioma, malignant

M8700/0 Pheochromocytoma, NOS (C74.1)

M8700/3 Pheochromocytoma, malignant (C74.1)

M8710/3 Glomangiosarcoma

M8711/0 Glomus tumor, NOS

M8711/3 Glomus tumor, Malignant

M8712/0 Glomangioma

M8713/0 Glomangiomyoma

872–879 Nevi And Melanomas

M8720/0 Pigmented nevus, NOS

M8720/2 Melanoma in situ

M8720/3 Malignant melanoma, NOS (except juvenile melanoma M8770/0)

M8721/3 Nodular melanoma

M8722/0 Balloon cell nevus

M8722/3 Balloon cell melanoma

M8723/0 Halo nevus

M8723/3 Malignant melanoma, regressing

M8725/0 Neuronevus

M8726/0 Magnocellular nevus (C69.4)

M8727/0 Dysplastic nevus

M8727/0 dysplastic nevus

M8728/0 Diffuse melanocytosis

M8728/1 Meningeal melanocytoma (C70.9)

M8728/3 Meningeal melanomatosis (C70.9)

M8730/0 Nonpigmented nevus

M8740/0 Junctional nevus, NOS

M8740/3 Malignant melanoma in junctional nevus

M8741/2 Precancerous melanosis, NOS

M8741/3 Malignant melanoma in precancerous melanosis

M8742/3 Lentigo maligna melanoma

M8743/3 Superficial spreading melanoma

M8744/3 Acral lentiginous melanoma, malignant

M8745/3 * Desmoplastic melanoma, malignant

M8746/3 Mucosal lentiginous melanoma

M8750/0 Intradermal nevus

M8760/0 compound nevus

M8761/0 Small congenital nevus

M8761/1 Giant pigmented nevus, NOS

M8761/3 Malignant melanoma in giant pigmented nevus/congenital melanocytic nevus

M78762/1 Proliferative dermal lesion in congenital nevus

M8770/0 Epithelioid and spindle cell nevus

M8770/3 Mixed epithelioid and spindle cell melanoma

M8771/0 Epithelioid cell nevus

M8771/3 Epithelioid cell melanoma

M8772/0 spindle cell nevus, NOS

M8772/3 Spindle cell melanoma, NOS

M8773/3 Spindle cell melanoma, type A

M8774/3 Spindle cell melanoma, type B

M8780/0 Blue nevus, NOS

M8780/3 blue nevus, malignant

M8790/0 Cellular blue nevus

880 Soft tissue Tumors And Sarcomas, NOS

M8800/0 Soft tissue tumor, benign

M8800/3 Sarcoma, NOS

M8800/9 Sarcomatosis, NOS

M8801/3 Spindle cell sarcoma

M8802/3 Giant cell sarcoma (except of bone M9250/3)

M8803/3 Small cell sarcoma

M8804/3 Epithelioid sarcoma

M8805/3 Undifferentiated sarcoma

M8806/3 Desmoplastic small round cell tumor

881–883 Fibromatous neoplasms

M8810/0 Fibroma, NOS

M8810/1 Cellular fibroma (C56.9)

M8810/3 Fibrosarcoma, NOS

M8811/0 Fibromyxoma

m8811/3 Fibromyxosarcoma

M8812/0 Periosteal fibroma (C40._, C41._)

M8813/0 Fascial fibroma

M8813/3 Fascial fibrosarcoma

M8814/3 Infantile fibrosarcoma

M8815/0 Solitary fibrous tumor

M8815/3 Solitary fibrous tumor, malignant

M8820/0 Elastofibroma

M8821/1 Aggressive fibromatosis

M8822/1 Abdominal fibromatosis

M8823/0 Desmoplastic fibroma

M8824/0 Myofibroma

M8824/1 Myofibromatosis

M8825/0 Myofibroblastoma

M8825/1 Myofibroblastic tumor, nos

M8826/0 Angiomyofibroblastoma

M8827/1 Myobfibroblastic tumor, peribronchial (C34._)

M8830/0 Benign fibrous histiocytoma

M8830/1 Atypical fibrous histiocytoma

M8830/3 Malignant fibrous histiocytoma

M8831/0 Histiocytoma, NOS

M8832/0 Dermatofibroma, NOS (C44._)

M8832/3 Dermatofibrosarcoma, NOS (C44._)

M8833/3 Pigmented dermatofibrosarcoma protuberans

M8834/1 Giant cell fibroblastoma

M8835/1 Plexiform fibrohistiocytic tumor

M8836/1 Angiomatoid fibrous histiocytoma

884 Myxomatous neoplasms

M8840/0 Myxoma, NOS

M8840/3 Myxosarcoma

M8841/1 Angiomyxoma

M8842/0 Ossifying fibromyxoid tumor

885–888 Lipomatous neoplasms

M8850/0 Lipoma, NOS

M8850/1 Atypical lipoma

M8850/3 Liposarcoma, NOS

M8851/0 Fibrolipoma

M8851/3 Liposarcoma, well differentiated

M8852/0 Fibromyxolipoma

M8852/3 Myxoid liposarcoma

M8853/3 Round cell liposarcoma

M8854/0 Pleomorphic lipoma

M8854/3 Pleomorphic liposarcoma

M8855/3 Mixed liposarcoma

M8856/0 Intramuscular lipoma

M8857/0 Spindle cell lipoma

M8857/3 Fibroblastic liposarcoma

M8858/3 Dedifferentiated liposarcoma

M8860/0 Angiomyolipoma

M8861/0 Angiolipoma, NOS

M8862/0 Chondroid lipoma

M8870/0 Myelolipoma

M8880/0 Hibernoma

M8881/0 Lipoblastomatosis

889–892 Myomatous neoplasms

M8890/0 Leiomyoma, NOS

M8890/1 Leiomyomatosis, NOS

M8890/3 Leiomyosarcoma, NOS

M8891/0 Epithelioid leiomyoma

M8891/3 Epithelioid leiomyosarcoma

M8892/0 Cellular leiomyoma

M8893/0 Bizarre leiomyoma

M8894/0 Angiomyoma

M8894/3 Angiomyosarcoma

M8895/0 Myoma

M8895/3 Myosarcoma

M8896/3 Myxoid leiomyosarcoma

M8897/1 Smooth muscle tumor of uncertain malignant potential

M8898/1 Metastasizing leiomyoma

M8900/0 Rhabdomyoma, NOS

M8900/3 Rhabdomyosarcoma, NOS

M8901/3 Pleomorphic rhabdomyosarcoma, adult type

M8902/3 Mixed type rhabdomyosarcoma

M8903/0 Fetal rhabdomyoma

M8904/0 Adult rhabdomyoma

M8905/0 Genital rhabdomyoma

M8910/3 Embryonal rhabdomyosarcoma, NOS

M8912/3 Spindle cell rhabdomyosarcoma

M8920/3 Alveolar rhabdomyosarcoma

M8921/3 Rhabdomyosarcoma with ganglionic differentiation

893–899 Complex Mixed And Stromal Neoplasms

M8930/0 Endometrial stromal nodule

M8930/3 Endometrial stromal sarcoma, NOS

M8931/3 Endometrial stromal sarcoma, low grade

M8932/0 Adenomyoma

M8933/3 Adenosarcoma

M8934/3 Carcinofibroma

M8935/0 Stromal tumor, benign

M9835/1 Stromal tumor, NOS

M8935/3 Stromal sarcoma, NOS

M8936/0 Gastrointestinal stromal tumor, benign

M8936/1 Gastrointestinal stromal tumor, NOS

M8936/3 Gastrointestinal stromal sarcoma

M8940/0 Pleomorphic adenoma

M8940/3 Mixed tumor, malignant, NOS

M8941/3 Carcinoma in pleomorphic adenoma

M8950/3 Mullerian mixed tumor

M8951/3 Mesodermal mixed tumor

M8959/0 Benign cystic nephroma

M8959/1 Cystic partially differentiated nephroblastoma

M8959/3 Malignant cystic nephroma

M8960/1 Mesoblastic nephroma

M8960/3 Nephroblastoma, NOS

M8963/3 malignant rhabdoid tumor

M8964/3 Clear cell sarcoma of kidney

M8965/0 Nephrogenic adenofibroma

M8966/0 Renomedullary interstitial cell tumor

M8967/0 Ossifying renal tumor

M8970/3 Hepatoblastoma

M8971/3 Pancreatoblastoma

M8972/3 Pulmonary blastoma

M8973/3 Pleuropulmonary blastoma

M8974/1 Sialoblastoma

M8980/3 Carcinosarcoma, NOS

M8981/3 Carcinosarcoma, embryonal

M8982/0 Myoepithelioma

M8982/3 Malignant myoepithelioma

M8983/0 Adenomyoepithelioma

M8990/0 Mesencymoma, benign

M8990/1 Mesenchymoma, NOS

M8990/3 Mesenchymoma, malignant

M8991/3 Embryonal sarcoma

9000–9030) Fibroepithelial Neoplasms

M9000/0 Brenner tumor, NOS

M9000/1 Brenner tumor, borderline malignancy

M9000/3 Brenner tumor, malignant

M9010/0 Fibroadenoma, NOS

M9011/0 Intracanalicular fibroadenoma

M9012/0 Pericanalicular fibroadenoma

M9013/0 Adenofibroma, NOS

M9014/0 Serous adenofibroma, NOS

M9014/1 Serous adenofibroma of borderline malignancy

M9014/3 Serous adenocarcinofibroma

M9015/0 Mucinous adenofibroma, NOS

M9015/1 Mucinous adenofibroma of borderline malignancy

M9015/3 Mucinous adenocarcinofibroma

M9016/0 Gian fibroadenoma

M9020/0 Phyllodes tumor, benign

M9020/1 Phyllodes tumor, borderline

M9020/3 Phyllodes tumor, malignant

M9030/0 Juvenile fibroadenoma

904 Synovial-Like Neoplasms

M9040/0 Synovioma, benign

M9040/3 Synovial sarcoma, NOS

M9041/3 Synovial sarcoma, spindle cell

M9042/3 Synovial sarcoma, epithelioid cell

M9043/3 Synovial sarcoma, biphasic

M9044/3 Clear cell sarcoma, NOS (except of kiney M9864/3)

905 Mesothelial Neoplasms

M9050/0 Mesothelioma, benign

M9050/3 Mesothelioma, malignant or NOS

M9051/0 Fibrous mesothelioma, benign

M9051/3 Fibrous mesothelioma, malignant or NOS

M9052/0 Epithelioid mesothelioma, benign

M9052/3 Epithelioid mesothelioma, malignant or NOS

M9053/3 Mesothelioma, biphasic, malignant or NOS

M9054/0 Adenomatoid tumor, NOS

M9055/0 Multicystic mesothelioma, benign

M9055/1 cystic mesothelioma, NOS

906–909 Germ cell Neoplasms

M9060/3 Dysgerminoma

M9061/3 Seminoma, NOS

M9062/3 Seminoma, anaplastic

M9063/3 Spermatocytic seminoma

M9064/2 Intratubular malignant germ cells

M9064/3 Germinoma

M9065/3 Germ cell tumor, nonseminomatous

M9070/3 Embryonal carcinoma, NOS

M9071/3 Yolk sac tumor

M9072/3 Polyembryoma

M9073/1 Gonadoblastoma

M9080/0 Teratoma, benign

M9080/1 Teratoma, NOS

M9080/3 Teratoma, malignant, NOS

M9081/3 Teratocarcinoma

M9082/3 malignant teratoma, undifferentiated

M9083/3 Malignant teratoma, intermediate

M9084/0 Dermoid cyst, NOS

M9084/3 Teratoma with malignant transformation

M9085/3 mixed germ cell tumor

M9090/0 Struma ovarii, NOS

M9090/3 Struma ovarii, malignant

M9091/1 Strumal carcinoid

910 Trophoblastic neoplasms

M9100/0 Hydatidifrom mole, NOS

M9100/1 Invasive hydatidiform mole

M9100/3 Choriocarcinoma, NOS

M9101/3 Choriocarcinoma combined with other germ cell elements

M9102/3 Malignant teratoma, trophoblastic

M9103/0 Partial hydatidiform mole

M9104/1 Placental site trophoblastic tumor

M9105/3 Trophoblastic tumor, epithelioid

911 Mesonephromas

M9110/0 Mesonephroma, benign

M9110/1 Mesonephric tumor, NOS

M9110/3 Mesonephroma, malignant

912–916 Blood vessel tumors

M9120/0 Hemangioma, NOS

M9120/3 Hemangiosarcoma

M9121/0 Cavernous hemangioma

M9122/0 Venous hemangioma

M9123/0 Racemose hemangioma

M9124/3 Kupffer cell sarcoma

M9125/0 Epithelioid hemangioma

M9130/0 Hemangioendothelioma, benign

M9130/1 Hemangioendothelioma, NOS

M9130/3 Hemangioendothelioma, malignant

M9131/0 Capillary hemangioma

M9132/0 Intramuscular hemangioma

M9133/1 Epithelioid hemangioendothelioma, NOS

M9133/3 Epithelioid hemangioendothelioma, malignant

M9135/1 Endovascular papillary angioendothelioma

M9136/1 Spindle cell hemangioendothelioma

M9140/3 Kaposi's sarcoma

M9141/0 Angiokeratoma

M9142/0 Verrucous keratotic hemangioma

M9150/0 Hemangiopericytoma, benign

M9150/1 Hemangiopericytoma, NOS

M9150/3 Hemangiopericytoma, malignant

M9160/0 angiofibroma, NOS

M9161/0 Acquired tufted hemangioma

M9161/1 Hemangioblastoma

M9150/0 Hemangiopericytoma, benign

M9150/1 Hemangiopericytoma, NOS

917 Lymphatic vessel tumors

M9170/0 Lymphangioma, NOS

M9170/3 Lymphangiosarcoma

M9171/0 Capillary lymphangioma

M9172/0 Cavernous lymphangioma

M9173/0 Cystic lymphangioma

M9174/0 Lymphangiomyoma

M9174/1 Lymphangiomyomatosis

M9175/0 Hemolymphangioma

918–924 Osseous And Chondromatous neoplasms

M9180/0 Osteoma, NOS

M9180/3 Osteosarcoma, NOS

M9181/3 Chondroblastic osteosarcoma

M9182/3 Fibroblastic osteosarcoma

M9183/3 Telangeictatic osteosarcoma

M9184/3 Osteosarcoma in Paget disease of bone

M9185/3 Small cell osteosarcoma

M9186/3 Central osteosarcoma

M9187/3 Intraosseous well differentiated osteosarcoma

M9191/0 Osteoid osteoma, NOS

M9192/3 Parosteal osteosarcoma

M9193/3 Periosteal osteosarcoma

M9194/3 High grade surface osteosarcoma

M9195/3 Intracortical osteosarcoma

M9200/0 Osteoblastmoa, NOS

M9200/1 Aggressive osetoblastoma

M9210/0 Osteochondroma

M9210/1 Osteochondromatosis, NOS

M9220/0 Chondroma, NOS

M9220/1 Condromatosis, NOS

M9220/3 Chondrosarcoma, NOS

M9221/0 Juxtacortical chondroma

M9221/3 Juxtacortical chondrosarcoma

M9230/0 Chondroblastoma, NOS

M9230/3 Chondroblastoma, malignant

M9231/3 Myxoid chondrosarcoma

M9240/3 Mesenchymal chondrosarcoma

M9241/0 Chondromyxoid fibroma

M9242/3 Clear cell chondrosarcoma

M9243/3 Dedifferentiated chondrosarcoma

925 Giant cell tumors

M9250/1 giant cell tumor of bone, NOS

M9250/3 Giant cell tumor of bone, malignant

M9251/1 Giant cell tumor of soft parts, NOS

M9251/3 Malignant giant cell tumor of soft parts

M9252/0 Tenosynovial giant cell tumor

M9252/3 Malignant tenosynovial giant cell tumoe

926 Miscellaneous bone tumors (C40._, C41._)

M9260/3 Ewing's sarcoma/tumor

M9261/3 Adamantinoma of long bones

M9262/0 Ossifying fibroma

927–934 Odontogenic tumors C41._)

M9270/0 Odontogenic tumor, benign

M9270/1 Odontogenic tumor, NOS

M9270/3 Odontogenic tumor, malignant

M9271/0 Ameloblastic fibrodentinoma

M9272/0 Cementoma, NOS

M9273/0 Cementoblastoma, benign

M9274/0 Cementifying fibroma

M9275/0 Gigantiform cementoma

M9280/0 Odontoma, NOS

M9281/0 Compound odontoma

M9282/0 Complex odontoma

M9290/0 Ameloblastic fibro-odontoma

M9290/3 Ameloblastic odontosarcoma

M9300/0 Adenomatoid odontogenic tumor

M9301/0 Calcifying odontogenic cyst

M9302/0 Odontogenic ghost cell tumor

M9310/0 Ameloblastoma, NOS

M9310/3 Ameloblastoma, malignant

M9311/0 Odontoameloblastoma

M9312/0 Squamous odontogenic tumor

M9320/0 Odontogenic myxoma

M9321/0 Central odontogenic fibroma

M9322/0 Peripheral odontogenic fibroma

M9330/0 Ameloblastic fibroma

M9330/3 Ameloblastic fibrosarcoma

M9340/0 Calcifying epithelial odontogenic tumor

M9341/1 clear cell odontogenic tumor

M9342/3 Odontogenic carcinosarcoma

935–937 Miscellaneous tumors

M9350/1 Craniopharyngioma

M9351/1 Craniopharyngioma, adamantinomatous

M9352/1 Craniopharyngioma, papillary

M9360/1 Pinealoma

M9361/1 Pineocytoma

M9362/3 Pineoblastoma

M9363/0 Melanotic neuroectodermal tumor

M9364/3 Peripheral neuroectodermal tumor

Peripheral primitive neuroectodermal tumor, NOS (PPNET)

M9365/3 Askin Tumor

M9370/3 Chordoma, NOS

M9371/3 Chondroid chordoma

M9372/3 Dedifferentiated chorcoma

M9373/0 Parachordoma

938–948 Gliomas

M9380/3 Glioma, malignant

M9381/3 Gliomatosis cerebri

M9382/3 Mixed glioma

M9383/1 Subepyndymoma

M9384/1 Subependymal giant cell astrocytoma

M9390/0 Choroid plexus papilloma, NOS

M9390/1 Atypical choroid plexus papilloma

M9390/3 Choroid plexus carcinoma

M9391/3 Ependymoma, NOS

M9392/3 Ependymoma, anaplastic

M9393/3 Papillary ependymoma

M9394/1 Myxopapillary ependymoma

M9400/3 Astrocytoma, NOS

M9401/3 Astrocytoma, anaplastic

M9410/3 Protoplasmic astrocytoma

M9411/3 Gemistocytic astrocytoma

M9412/1 Desmoplastic infantile astrocytoma or ganglioglioma

M9413/0 dysembryoplastic neuroepithelial tumor

M9420/3 Fibrillary astrocytoma

M9421/1 Pilocytic astrocytoma

M9423/3 Polar spongioblastoma

M9424/3 Pleomorphic xanthoastrocytoma

M9430/3 Astroblastoma

M9440/3 Glioblastoma, NOS

M9441/3 Giant cell glioblastoma

M9442/1 gliofibroma

M9442/3 gliosarcoma

M9444/1 Chordoid glioma

M9450/3 Oligodendroglioma, NOS

M9451/3 Oligodendroglioma, anaplastic

M9460/3 Oligodendroblastoma

M9470/3 Medullablastoma, NOS

M9471/3 Desmoplastic nodular medulloblastoma

M9472/3 Medullomyoblastoma

M9473/3 Primitive neuroectodermal tumor, NOS

M9474/3 large cell medulloblastoma

M9480/3 Cerebellar sarcoma, NOS

949–952 Neuroepitheliomatous neoplasms

M9490/0 Ganglioneuroma

M9490/3 Ganglioneuroblastoma

M9491/0 Ganglioneuromatosis

M9492/0 Gangliocytoma

M9493/0 Dysplastic gangliocytoma of cerebellum (Lhermitte-Duclos)

M9500/3 Neuroblastoma, NOS

M9501/0 Medulloepithelioma, benign

M9501/3 Medulloepithelioma, NOS

M9502/0 Teratoid medulloepithelioma, benign

M9502/3 Teratoid medulloepithelioma

M9503/3 Neuroepithelioma, NOS

M9504/3 Spongioneuroblastoma

M9505/1 Ganglioglioma, NOS

M9505/3 Ganglioglioma, anaplastic

M9506/1 Central neurocytoma

M9507/0 Pacinian tumor

M9508/3 Atypical teratoid/rhabdoid tumor

M9510/0 Retinocytoma

M9510/3 Retinoblastoma, NOS

M9511/3 Retinoblastoma, differentiated

M9512/3 Retinoblastoma, undifferentiated

M9513/3 Retinoblastoma, diffuse

M9514/1 Retinoblastoma, spontaneously regressed

M9520/3 Olfactory neurogenic tumor

M9521/3 Olfactory neurocytoma

M9522/3 Olfactory neuroblastoma

M9523/3 Olfactory neuroepithelioma

953 Meningiomas

M9530/0 Meningioma, NOS

M9530/1 Meningiomatosis, NOS

M9530/3 Meningioma, malignant

M9531/0 Meningothelial meningioma

M9532/0 Fibrous meningioma

M9533/0 Psammomatous meningioma

M9534/0 Angiomatous meningioma

M9537/0 Transitional meningioma

M9538/1 Clear cell meningioma

M9538/3 Papillary meningioma

M9539/1 Atypical meningioma

M9539/3 Meningeal sarcomatosis

954–957 Nerve sheath tumors

M9540/0 Neurofibroma, NOS

M9540/1 Neurofibromatosis, NOS

M9540/3 Malignant peripheral nerve sheath tumor

M9541/0 Melanotic neurofibroma

M9550/0 Plexiform neurofibroma

M9560/0 Neurilemoma, NOS

M9560/1 Neurinomatosis

M9561/3 Malignant peripheral nerve sheath tumor with rhabdomyoblastic differentiation

M9562/0 Neurothekeoma

M9570/0 Neuroma, NOS

M9571/0 Perineurioma, NOS

M9571/3 Perineurioma, malignant

M9560/0 Schwannoma, NOS

M9560/0 Neurinoma

M9560/0 Acoustic neuroma

M9570/0 Neuroma, NOS

958 Granular cell tumors and Alveolar soft part sarcoma

M9580/0 Granular cell tumor/myoblastoma, NOS

M9580/3 Granular cell tumor/myoblastoma, malignant

M9581/3 Alveolar soft part sarcoma

M9582/0 Granular cell tumor of the sellar region (C75.1)

959 Malignant lymphoma, NOS, Or diffuse

M9590/3 Malignant Lymphoma, NOS

M9591/3 Malignant lymphoma, non-Hodgkin, NOS

M9596/3 Composite Hodgkin and non-Hodgkin lymphoma

965–966 Hodgkin Lymphoma

M9650/3 Hodgkin lymphoma, NOS

M9651/3 Hodgkin lymphoma, lymphocyte rich

M9652/3 Mixed cellularity classical Hodgkin lymphoma, NOS

M9653/3 Lymphocyte-depleted classical Hodgkin lymphoma, NOS

M9654/3 Hodgkin lymphoma, lymphocyte depletion, diffuse fibrosis

M9655/3 Hodgkin lymphoma, lymphocyte depletion, reticular

M9659/3 Nodular lymphocyte predominant Hodgkin lymphoma

M9661/3 Hodgkin granuloma

M9662/3 Hodgkin sarcoma

M9663/3 Nodular sclerosis classical Hodgkin lymphoma

M9664/3 Hodgkin lymphoma, nodular sclerosis, cellular phase

M9665/3 Hodgkin lymphoma, nodular sclerosis, grade 1

M9667/3 Hodgkin lymphoma, nodular sclerosis, grade 2

967-969 Mature B-cell Lymphomas

M9670/3 Malignant lymphoma, small B lymphocytic, NOS (see also M9823/3)

M9671/3 Malignant lymphoma, lymphoplasmacytic (see also M9761/3)

M9673/3 Mantle cell lymphoma

M9675/3 Malignant lymphoma, mixed small and large cell, diffuse (see also M9690/3)

M9678/3 Primary effusion lymphoma

M9679/3 Mediastinal large B-cell lymphoma (C38.3)

M9680/3 Malignant lymphoma, large B-cell, diffuse, NOS

M9684/3 Malignant lymphoma, large B-cell, diffuse, immunoblastic, NOS

M9687/3 Burkitt lymphoma, NOS (see also M9826/3)

M9689/3 Splenic marginal zone lymphoma

M9690/3 Follicular lymphoma, NOS (see also M9675/3)

M9691/3 Follicular lymphoma, grade 2

M9698/3 Follicular lymphoma, grade 3

M9699/3 Marginal zone B-cell lymphoma, NOS

970–971 Mature T- and NK-cell Lymphomas

M9700/3 Mycosis fungoides

M9701/3 Sezary syndrome

M9702/3 Mature T-cell lymphoma, NOS

M9705/3 Angioimmunoblastic T-cell lymphoma

M9708/3 Subcutaneous panniculitis-like T-cell lymphoma

M9709/3 Cutaneous T-cell lymphoma, NOS (C44._)

M9714/3 Anaplastic large cell lymphoma, T cell and Null cell type

M9716/3 Hepatosplenic (gamma-delta) cell lymphoma

M9717/3 Intestinal T-cell lymphoma

M9718/3 Primary cutaneous CD 30+ T-cell lymphoproliferative disorder (C44._)

M9719/3 NK/T-cell lymphoma, nasal and nasal type

972 Precursor Cell Lymphoblastic Lymphoma

M9727/3 Precursor cell lymphoblastic lymphoma, NOS (see also M9835/3)

M9728/3 Precursor B-cell lymphoblastic Lymphoma (see also M9836/3)

M9729/3 Precursor T-cell lymphoblastic Lymphoma (see also M9837/3)

973 Plasma cell tumors

M9731/3 Plasmacytoma, NOS

M9732/3 Multiple myeloma (C42.1)

M9733/3 Plasma cell leukemia (C42.1)

M9734/3 Plasmacytoma, extramedullary (not occurring in bone)

974 Mast cell Tumors

M9740/1 Mastocytoma, NOS or Extracutaneous mastocytoma

M9740/3 Mast cell sarcoma

M9741/3 Malignant mastocytosis

M9742/3 Mast cell leukemia (C42.1)

975 Neoplasms of Histiocytes and Accessory Lymphoid Cells

M9750/3 Malignant histiocytosis

M9751/1 Langerhans cell histiocytosis, NOS

M9752/1 Langerhans cell histiocytosis, unifocal

M9753/1 Langerhans cell histiocytosis, multifocal

M9754/3 Langerhans cell histiocytosis, disseminated

M9755/3 Histiocytic sarcoma

M9756/3 Langerhans cell sarcoma

M9757/3 Dendritic cell sarcoma, NOS

M9758/3 Follicular dendritic cell sarcoma/tumor

976 Immunoproliferative diseases

M9760/3 Immunoproliferative disease, NOS

M9761/3 Waldenstrom macroglobulinemia (C42.0) (see also M9671/3)

M9762/3 Heavy chain disease, NOS

M9764/3 Immunoproliferative small intestinal disease (C17._)

M9765/1 Monoclonal gammopathy of undetermined significance

(M9766/1) Angiocentric immunoproliferative lesion

M9767/1 Angioimmunoblastic lymphadenopathy

M9768/1 T-gamma lymphoproliferative disease

M9769/1 Immunoglobulin deposition disease

980) Leukemias, NOS

M9800/3 Leukemia, NOS

M9801/3 Acute leukemia, NOS

M9805/3 Acute biphenotypic leukemia

(982–983) Lymphoid leukemias (C42.1)

M9820/3 Lymphoid leukemia, NOS

M9823/3 B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma (see also M9670/3)

M9826/3 Burkitt cell Leukemia (see also M9687/3)

M9827/3 Adult T-cell leukemia/lymphoma (HTLV-1 positive) includes all variants

M9831/1 T-cell large granular lymphocytic leukemia

M9832/3 Prolymphocytic leukemia, NOS

M9833/3 B-cell prolymphocytic leukemia

M9834/3 T-cell prolymphocytic leukemia

M9835/3 Precursor cell lymphoblastic leukemia, NOS (see also M9727/3)

M9836/3 Precursor B lymphoblastic leukemia (see also M9728/3)

M9837/3 Precursor T lymphoblastic leukemia (see also M9729/3)

984-993 Myeloid Leukemias (C42.1)

(9840–9849) Erythroleukemias (FAB-M6)

M9840/3 Acute myeloid leukemia, M6 type

(9850–9859) Lymphosarcoma cell leukemia (9860–9869) Myeloid (Granulocytic) Leukemias

M9860/3 Myeloid leukemia, NOS

M9861/3 Acute myeloid leukemia, NOS (FAB or WHO type not specified (see also M9930/3)

M9863/3 Chronic myeloid leukemia, NOS

M9866/3 Acute promyelocytic leukemia t(15;17)(q22;q11-12) * Acute promyelocytic leukemia, PML/RAR-alpha

FAB-M3 (includes all variants)

M9867/3) Acute myelomonocytic leukemia

M9870/3 Basophilic leukemia or Acute basophilic leukemia

M9871/3 Acute myeloid leukemia with abnormal marrow eosinophils (includes all variants)

M9872/3 Acute myeloid leukemia, minimally differentiated (FAB type M0)

M9873/3 Acute myeloid leukemia, without maturation (FAB type M1)

M9874/3 Acute myeloid leukemia, with maturation (FAB M2), NOS

M9875/3 Chronic myelogenous leukemia BCR/ABL positive

M9876/3 Atypical chronic myelogenous leukemia BCR/ABL negative

M9891/3 Acute monoblastic and monocytic leukemia

M9895/3 Acute myeloid leukemia multilineage dysplasia

M9896/3 AML with t(8;21)(q22;q22), AML1/ETO

M9897/3 AML with 11q23 (MLL) abnormalities

M9910/3 Acute megakaryoblastic leukemia, NOS

M9920/3 Acute myeloid leukemia and myelodysplastic syndrome, therapy related, NOS Therapy-related acute myeloid leukemia, alkylating agent/epipodophyllotoxin related

M9930/3 Chloroma or Myeloid sarcoma (see also M9861/3)

M9931/3) Acute panmyelosis with myelofibrosis (C42.1)

994 Other Leukemias (C42.1)

M9940/3 Hairy cell leukemia (C42.1)

M9945/3 Chronic myelomonocytic, leukemia, NOS

M9946/3 Juvenile myelomonocytic leukemia

M9948/3 Aggressive NK cell leukemia

995-996 Chronic Myeloproliferative Disorders (C42.1)

M9950/3 Polycythemia vera

M9960/1 Chronic Myeloproliferative disease, NOS

M9961/3 Myelosclerosis with myeloid metaplasia

M9962/3 Essential thrombocytemia

M9963/3 Chronic neutrophilic leukemia

M9964/3 Chronic eosinophilic leukemia / hypereosinophilic syndrome

997 Other Haematologic Disorders

M9970/1 Lymphoproliferative disease/disorder, NOS

M9775/1 Myeloproliferative disease, NOS

998 Myelodysplastic syndrome (C42.1)

M9980/3 Chronic myelomonocytic leukemia or Refractory anemia

M9982/3 Refractory anemia with ringed sideroblasts

M9983/3 Refractory anemia with excess blasts

M9985/3 Refractory cytopenia with multilineage dysplasia

M9986/3 Myelodysplastic syndrome associated with isolated del(5q) chromosome abnormality

M9989/3 Myelodysplastic syndrome, NOS

See also

References

  1. International Classification of Diseases for Oncology; Third edition; World Health Organization; Reprinted 2001; Fritz, Percy, Jack, Shanmugaratnam, Sobin, Parkin, Whelan

Morphology

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