PRSS22

PRSS22
Identifiers
Aliases PRSS22, BSSP-4, hBSSP-4, SP001LA, protease, serine 22
External IDs MGI: 1918085 HomoloGene: 23344 GeneCards: PRSS22
Orthologs
Species Human Mouse
Entrez

64063

70835

Ensembl

n/a

ENSMUSG00000045027

UniProt

Q9GZN4

Q9ER10

RefSeq (mRNA)

NM_022119

NM_133731

RefSeq (protein)

NP_071402.1

NP_598492.2

Location (UCSC) Chr 16: 2.85 – 2.86 Mb Chr 17: 23.99 – 24 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

Brain-specific serine protease 4 (BSSP-4), also known as serine protease 22 or tryptase epsilon, is an enzyme that in humans is encoded by the PRSS22 gene.[3][4][5]

This gene encodes a member of the trypsin family of serine proteases. The enzyme is expressed in the airways in a developmentally regulated manner. The gene is part of a cluster of serine protease genes on chromosome 16.[3]

See also

References

  1. "Human PubMed Reference:".
  2. "Mouse PubMed Reference:".
  3. 1 2 "Entrez Gene: protease".
  4. Wong GW, Yasuda S, Madhusudhan MS, Li L, Yang Y, Krilis SA, Sali A, Stevens RL (December 2001). "Human tryptase epsilon (PRSS22), a new member of the chromosome 16p13.3 family of human serine proteases expressed in airway epithelial cells". J. Biol. Chem. 276 (52): 49169–82. doi:10.1074/jbc.M108677200. PMID 11602603.
  5. Yasuda S, Morokawa N, Wong GW, Rossi A, Madhusudhan MS, Sali A, Askew YS, Adachi R, Silverman GA, Krilis SA, Stevens RL (May 2005). "Urokinase-type plasminogen activator is a preferred substrate of the human epithelium serine protease tryptase epsilon/PRSS22". Blood. 105 (10): 3893–901. doi:10.1182/blood-2003-10-3501. PMC 1895090Freely accessible. PMID 15701722.

Further reading


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