Post-translational regulation

Post-translational regulation refers to the control of the levels of active protein.

There are several forms.^[1]

It is performed either by means of reversible events (posttranslational modifications, such as phosphorylation or sequestration) or by means of irreversible events (proteolysis).

References

↑ Wolfgang Schumann; Wolfgang Schumann (Prof. Dr. rer. nat.) (2006). Dynamics of the bacterial chromosome: structure and function. Wiley-VCH. pp. 266–. ISBN 978-3-527-30496-7. Retrieved 26 December 2010.

Types	Bacterial Eukaryotic

Key elements	Transcription factor RNA polymerase Promoter

Post-transcription	Precursor mRNA (pre-mRNA / hnRNA) 5' capping Splicing Polyadenylation Histone acetylation and deacetylation

Types	Prokaryotic Eukaryotic

Key elements	Ribosome Transfer RNA (tRNA) Ribosome-nascent chain complex (RNC) Post-translational modification (functional groups · peptides · structural changes)

Influential people

Overview

Central dogma	History of molecular biology DNA replication (DNA) Transcription (RNA) Translation (protein)

Element	Genetic Heredity Promoter Pribnow box TATA box Operon gal operon lac operon trp operon Intron Exon Terminator Enhancer Repressor lac repressor trp repressor Silencer Histone methylation

Linked life	Cell biology Biochemistry Computational biology Genetics

Engineering

Concepts	Mitosis Cell signalling Post-transcriptional modification Post-translational modification Dry lab / Wet lab

Techniques	Cell culture Model organisms (such as C57BL/6 mice) Methods Nucleic acid Protein Fluorescence, Pigment & Radioactivity High-throughput technique ("-omics") DNA microarray Mass spectrometry Lab-on-a-chip

Gene regulation	Epigenetic Genetic Post-transcriptional Post-translational regulation

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