SLC25A3

SLC25A3
Identifiers
Aliases SLC25A3, PHC, PTP, OK/SW-cl.48, solute carrier family 25 member 3
External IDs MGI: 1353498 HomoloGene: 37649 GeneCards: SLC25A3
Orthologs
Species Human Mouse
Entrez

5250

18674

Ensembl

ENSG00000075415

ENSMUSG00000061904

UniProt

Q00325

Q8VEM8

RefSeq (mRNA)

NM_213612
NM_002635
NM_005888
NM_213611

NM_133668

RefSeq (protein)

NP_002626.1
NP_005879.1
NP_998776.1
NP_005879.1

NP_598429.1

Location (UCSC) Chr 12: 98.59 – 98.61 Mb Chr 10: 91.12 – 91.12 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

Phosphate carrier protein, mitochondrial is a protein that in humans is encoded by the SLC25A3 gene.[3][4]

The protein encoded by this gene catalyzes the transport of phosphate into the mitochondrial matrix, either by proton cotransport or in exchange for hydroxyl ions. The protein contains three related segments arranged in tandem which are related to those found in other characterized members of the mitochondrial carrier family. Both the N-terminal and C-terminal regions of this protein protrude toward the cytosol. Multiple alternatively spliced transcript variants have been isolated.[4]

See also

References

  1. "Human PubMed Reference:".
  2. "Mouse PubMed Reference:".
  3. Jabs EW, Thomas PJ, Bernstein M, Coss C, Ferreira GC, Pedersen PL (Jun 1994). "Chromosomal localization of genes required for the terminal steps of oxidative metabolism: alpha and gamma subunits of ATP synthase and the phosphate carrier". Hum Genet. 93 (5): 600–2. doi:10.1007/bf00202832. PMID 8168843.
  4. 1 2 "Entrez Gene: SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3".

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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