UBP-302

UBP-302

Names
IUPAC name 2-{[3-[(2S)-2-amino-2-carboxyethyl]-2,6-dioxo-3,6-dihydropyrimidin-1(2H)-yl]methyl}benzoic acid
Identifiers
CAS Number	745055-91-8
3D model (Jmol)	Interactive image
ChEMBL	ChEMBL372797
ChemSpider	4925720
ECHA InfoCard	100.210.061
PubChem	6420161
InChI InChI=1S/C15H15N3O6/c16-11(14(22)23)8-17-6-5-12(19)18(15(17)24)7-9-3-1-2-4-10(9)13(20)21/h1-6,11H,7-8,16H2,(H,20,21)(H,22,23)/t11-/m0/s1 Key: UUIYULWYHDSXHL-NSHDSACASA-N InChI=1/C15H15N3O6/c16-11(14(22)23)8-17-6-5-12(19)18(15(17)24)7-9-3-1-2-4-10(9)13(20)21/h1-6,11H,7-8,16H2,(H,20,21)(H,22,23)/t11-/m0/s1 Key: UUIYULWYHDSXHL-NSHDSACABL
SMILES c1ccc(c(c1)Cn2c(=O)ccn(c2=O)C[C@@H](C(=O)O)N)C(=O)O
Properties
Chemical formula	C15H15N3O6
Molar mass	333.296 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

UBP-302 is a highly selective kainate receptor antagonist used in the study of many neurological processes. It is active at micromolar concentration within an in vitro preparation and specifically targets the GluR5 subunit of the receptor. This compound was developed at the University of Bristol.^[1]

References

1. More, JC; Nistico, R; Dolman, NP; Clarke, VR; Alt, AJ; Ogden, AM; Buelens, FP; Troop, HM; et al. (2004). "Characterisation of UBP296: a novel, potent and selective kainate receptor antagonist". Neuropharmacology. 47 (1): 46–64. doi:10.1016/j.neuropharm.2004.03.005. PMID 15165833.