JTE 7-31

JTE 7-31

Names
IUPAC name 2-[2-(4-hydroxyphenyl)ethyl]-5-methoxy-4-(pentylamino)-2,3-dihydro-1H-isoindol-1-one
Identifiers
CAS Number	194358-72-0
3D model (Jmol)	Interactive image
ChemSpider	13767708
PubChem	19363402
InChI InChI=1S/C22H28N2O3/c1-3-4-5-13-23-21-19-15-24(14-12-16-6-8-17(25)9-7-16)22(26)18(19)10-11-20(21)27-2/h6-11,23,25H,3-5,12-15H2,1-2H3 Key: FMUMUYFMLZGXJR-UHFFFAOYSA-N InChI=1/C22H28N2O3/c1-3-4-5-13-23-21-19-15-24(14-12-16-6-8-17(25)9-7-16)22(26)18(19)10-11-20(21)27-2/h6-11,23,25H,3-5,12-15H2,1-2H3 Key: FMUMUYFMLZGXJR-UHFFFAOYAA
SMILES Oc1ccc(cc1)CCN3Cc2c(ccc(OC)c2NCCCCC)C3=O
Properties
Chemical formula	C22H28N2O3
Molar mass	368.469 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

JTE 7-31 is a selective cannabinoid receptor agonist invented by Japan Tobacco.^[1][2] It is a reasonably highly selective CB₂ agonist, but still retains appreciable affinity at CB₁, with a K_i of 0.088nM at CB₂ vs 11nM at CB₁.

Legality

JTE 7-31 is illegal in Alabama.^[3]

See also

• A-834,735
• JTE-907
• MDA-19
• N-(S)-Fenchyl-1-(2-morpholinoethyl)-7-methoxyindole-3-carboxamide
• S-444,823
• XLR-12

References

1. WO patent 1997/029079, Inaba T, Kaya T, Iwamura H, "Novel compounds and pharmaceutical use thereof", granted 1997-14-08 
2. US patent 6017919, Inaba T, Kaya T, Iwamura H, "Compounds and pharmaceutical use thereof", granted 2000-01-25 
3. Alabama Senate Bill SB 333: Controlled Substances