KRT36
KRT36 | |||||||||||||||||
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Identifiers | |||||||||||||||||
Aliases | KRT36, HA6, KRTHA6, hHa6, keratin 36 | ||||||||||||||||
External IDs | MGI: 109364 HomoloGene: 88459 GeneCards: KRT36 | ||||||||||||||||
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RNA expression pattern | |||||||||||||||||
More reference expression data | |||||||||||||||||
Orthologs | |||||||||||||||||
Species | Human | Mouse | |||||||||||||||
Entrez | |||||||||||||||||
Ensembl | |||||||||||||||||
UniProt | |||||||||||||||||
RefSeq (mRNA) | |||||||||||||||||
RefSeq (protein) | |||||||||||||||||
Location (UCSC) | Chr 17: 41.49 – 41.49 Mb | Chr 11: 100.1 – 100.11 Mb | |||||||||||||||
PubMed search | [1] | [2] | |||||||||||||||
Wikidata |
View/Edit Human | View/Edit Mouse |
Keratin, type I cuticular Ha6 is a protein that in humans is encoded by the KRT36 gene.[3][4][5]
The protein encoded by this gene is a member of the keratin gene family. This type I hair keratin is an acidic protein which heterodimerizes with type II keratins to form hair and nails. The type I hair keratins are clustered in a region of chromosome 17q12-q21 and have the same direction of transcription.[5]
References
- ↑ "Human PubMed Reference:".
- ↑ "Mouse PubMed Reference:".
- ↑ Rogers MA, Winter H, Wolf C, Heck M, Schweizer J (Nov 1998). "Characterization of a 190-kilobase pair domain of human type I hair keratin genes". J Biol Chem. 273 (41): 26683–91. doi:10.1074/jbc.273.41.26683. PMID 9756910.
- ↑ Schweizer J, Bowden PE, Coulombe PA, Langbein L, Lane EB, Magin TM, Maltais L, Omary MB, Parry DA, Rogers MA, Wright MW (Jul 2006). "New consensus nomenclature for mammalian keratins". J Cell Biol. 174 (2): 169–74. doi:10.1083/jcb.200603161. PMC 2064177. PMID 16831889.
- 1 2 "Entrez Gene: KRT36 keratin 36".
Further reading
- Fuchs E, Weber K (1994). "Intermediate filaments: structure, dynamics, function, and disease.". Annu. Rev. Biochem. 63: 345–82. doi:10.1146/annurev.bi.63.070194.002021. PMID 7979242.
- Yu J, Yu DW, Checkla DM, et al. (1993). "Human hair keratins.". J. Invest. Dermatol. 101 (1 Suppl): 56S–59S. doi:10.1111/1523-1747.ep12362635. PMID 7686952.
- Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry.". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
- Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Langbein L, Rogers MA, Winter H, et al. (1999). "The catalog of human hair keratins. I. Expression of the nine type I members in the hair follicle.". J. Biol. Chem. 274 (28): 19874–84. doi:10.1074/jbc.274.28.19874. PMID 10391933.
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