MYO1B

MYO1B
Identifiers
Aliases	MYO1B, myr1, myosin IB
External IDs	MGI: 107752 HomoloGene: 7856 GeneCards: MYO1B
Genetically Related Diseases
obesity[1]
Gene ontology Molecular function • nucleotide binding • actin-dependent ATPase activity • calmodulin binding • actin filament binding • microfilament motor activity • actin binding • phosphatidylinositol-4,5-bisphosphate binding • motor activity • ATP binding • phosphatidylinositol-3,4,5-trisphosphate binding • cadherin binding involved in cell-cell adhesion Cellular component • cytoplasm • trans-Golgi network membrane • filopodium • plasma membrane • early endosome • brush border • actin filament • perinuclear region of cytoplasm • endosome membrane • extracellular exosome • cell periphery • myosin complex • cell-cell adherens junction Biological process • actin filament organization • actin filament-based movement • actin filament bundle assembly • post-Golgi vesicle-mediated transport • cell-cell adhesion Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	4430	17912
Ensembl	ENSG00000128641	ENSMUSG00000018417
UniProt	O43795	P46735
RefSeq (mRNA)	NM_001130158 NM_001161819 NM_012223	NM_001161817 NM_001290982 NM_010863
RefSeq (protein)	NP_001123630.1 NP_001155291.1 NP_036355.2	NP_034993.2
Location (UCSC)	Chr 2: 191.25 – 191.43 Mb	Chr 1: 51.75 – 51.92 Mb
PubMed search	[2]	[3]
Wikidata

View/Edit Human

View/Edit Mouse

Myosin-Ib is a protein that in humans is encoded by the MYO1B gene.^[4][5][6]

References

1. "Diseases that are genetically associated with MYO1B view/edit references on wikidata".
2. "Human PubMed Reference:".
3. "Mouse PubMed Reference:".
4. Bement WM, Hasson T, Wirth JA, Cheney RE, Mooseker MS (Aug 1994). "Identification and overlapping expression of multiple unconventional myosin genes in vertebrate cell types". Proc Natl Acad Sci U S A. 91 (14): 6549–53. doi:10.1073/pnas.91.14.6549. PMC 44240. PMID 8022818.
5. Ruppert C, Kroschewski R, Bahler M (Apr 1993). "Identification, characterization and cloning of myr 1, a mammalian myosin-I". J Cell Biol. 120 (6): 1393–403. doi:10.1083/jcb.120.6.1393. PMC 2119751. PMID 8449985.
6. "Entrez Gene: MYO1B myosin IB".

Further reading

• Ruppert C, Godel J, Müller RT, et al. (1997). "Localization of the rat myosin I molecules myr 1 and myr 2 and in vivo targeting of their tail domains". J. Cell. Sci. 108 (12): 3775–86. PMID 8719884.
• Tang N, Ostap EM (2001). "Motor domain-dependent localization of myo1b (myr-1)". Curr. Biol. 11 (14): 1131–5. doi:10.1016/S0960-9822(01)00320-7. PMID 11509238.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Dumont RA, Zhao YD, Holt JR, et al. (2003). "Myosin-I isozymes in neonatal rodent auditory and vestibular epithelia". J. Assoc. Res. Otolaryngol. 3 (4): 375–89. doi:10.1007/s101620020049. PMC 3202438. PMID 12486594.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Salas-Cortes L, Ye F, Tenza D, et al. (2006). "Myosin Ib modulates the morphology and the protein transport within multi-vesicular sorting endosomes". J. Cell. Sci. 118 (Pt 20): 4823–32. doi:10.1242/jcs.02607. PMID 16219689.
• Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein–protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.