16β,17α-Epiestriol
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| Names | |
|---|---|
| IUPAC name
(8R,9S,13S,14S,16S,17S)-13-Methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,16,17-triol | |
| Identifiers | |
| 793-89-5 | |
| 3D model (Jmol) | Interactive image |
| ChemSpider | 13628086 |
| PubChem | 21252247 |
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| Properties | |
| C18H24O3 | |
| Molar mass | 288.39 g·mol−1 |
| Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| Infobox references | |
16β,17α-Epiestriol, or 16,17-epiestriol, also known as 16β-hydroxy-17α-estradiol, as well as estra-1,3,5(10)-triene-3,16β,17α-triol, is a minor and weak endogenous steroidal estrogen that is related to 17α-estradiol and estriol.[1][2] Along with estriol, 16β,17α-epiestriol has been detected in the urine of women during the late pregnancy stage.[2] It shows preferential affinity for the ERβ over the ERα.[3]
See also
References
- ↑ Vitamins and Hormones. Academic Press. 18 April 1972. pp. 233–. ISBN 978-0-08-086626-0.
- 1 2 Ryō Satō; Ryūichi Katō (1982). Microsomes, drug oxidations, and drug toxicity. Japan Scientific Societies Press. p. 273. ISBN 978-0-471-87285-6.
- ↑ Zhu BT, Han GZ, Shim JY, Wen Y, Jiang XR (2006). "Quantitative structure-activity relationship of various endogenous estrogen metabolites for human estrogen receptor alpha and beta subtypes: Insights into the structural determinants favoring a differential subtype binding". Endocrinology. 147 (9): 4132–50. doi:10.1210/en.2006-0113. PMID 16728493.
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