AQP7

AQP7
Identifiers
Aliases AQP7, AQP7L, AQP9, AQPap, GLYCQTL, aquaporin 7
External IDs MGI: 1314647 HomoloGene: 48000 GeneCards: AQP7
RNA expression pattern
More reference expression data
Orthologs
Species Human Mouse
Entrez

364

11832

Ensembl

ENSG00000165269

ENSMUSG00000028427

UniProt

O14520

O54794

RefSeq (mRNA)

NM_001170
NM_001318156
NM_001318157
NM_001318158

NM_007473

RefSeq (protein)

NP_001161.1
NP_001305086.1
NP_001305087.1

NP_031499.1

Location (UCSC) Chr 9: 33.38 – 33.4 Mb Chr 4: 41.03 – 41.05 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

Aquaporin-7 is a protein that in humans is encoded by the AQP7 gene.[3][4]

Aquaporins/major intrinsic protein (MIP) are a family of water-selective membrane channels. Aquaporin 7 has greater sequence similarity with AQP3 and AQP9 and they may be a subfamily. Aquaporin 7 and AQP3 are at the same chromosomal location suggesting that 9p13 may be a site of an aquaporin cluster. Aquaporin 7 facilitates water, glycerol and urea transport. It may play an important role in sperm function.[4]

See also

References

  1. "Human PubMed Reference:".
  2. "Mouse PubMed Reference:".
  3. Ishibashi K, Kuwahara M, Gu Y, Kageyama Y, Tohsaka A, Suzuki F, Marumo F, Sasaki S (Sep 1997). "Cloning and functional expression of a new water channel abundantly expressed in the testis permeable to water, glycerol, and urea". J Biol Chem. 272 (33): 20782–6. doi:10.1074/jbc.272.33.20782. PMID 9252401.
  4. 1 2 "Entrez Gene: AQP7 aquaporin 7".

Further reading

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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