GJA10
GJA10 | |||||||||||||||||
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Identifiers | |||||||||||||||||
Aliases | GJA10, CX62, gap junction protein alpha 10 | ||||||||||||||||
External IDs | MGI: 1339969 HomoloGene: 7733 GeneCards: GJA10 | ||||||||||||||||
Targeted by Drug | |||||||||||||||||
carbenoxolone, flufenamic acid, caprylic alcohol[1] | |||||||||||||||||
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Orthologs | |||||||||||||||||
Species | Human | Mouse | |||||||||||||||
Entrez | |||||||||||||||||
Ensembl | |||||||||||||||||
UniProt | |||||||||||||||||
RefSeq (mRNA) | |||||||||||||||||
RefSeq (protein) | |||||||||||||||||
Location (UCSC) | Chr 6: 89.89 – 89.9 Mb | Chr 4: 32.6 – 32.6 Mb | |||||||||||||||
PubMed search | [2] | [3] | |||||||||||||||
Wikidata |
View/Edit Human | View/Edit Mouse |
Gap junction alpha-10 protein, also known as connexin-62 (Cx62), is a protein that in humans is encoded by the GJA10 gene.[4]
Connexins, such as GJA10, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits.[4][5]
References
- ↑ "Drugs that physically interact with Gap junction alpha-10 protein view/edit references on wikidata".
- ↑ "Human PubMed Reference:".
- ↑ "Mouse PubMed Reference:".
- 1 2 "Entrez Gene: gap junction protein".
- ↑ Söhl G, Nielsen PA, Eiberger J, Willecke K (2003). "Expression profiles of the novel human connexin genes hCx30.2, hCx40.1, and hCx62 differ from their putative mouse orthologues". Cell Commun. Adhes. 10 (1): 27–36. doi:10.1080/15419060302063. PMID 12881038.
Further reading
- Hosgood HD, Zhang L, Shen M, et al. (2009). "Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity.". Occup Environ Med. 66 (12): 848–53. doi:10.1136/oem.2008.044024. PMC 2928224. PMID 19773279.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.