GJA10

GJA10
Identifiers
Aliases GJA10, CX62, gap junction protein alpha 10
External IDs MGI: 1339969 HomoloGene: 7733 GeneCards: GJA10
Targeted by Drug
carbenoxolone, flufenamic acid, caprylic alcohol[1]
Orthologs
Species Human Mouse
Entrez

84694

14610

Ensembl

ENSG00000135355

ENSMUSG00000051056

UniProt

Q969M2

Q9WUS4

RefSeq (mRNA)

NM_032602

NM_010289

RefSeq (protein)

NP_115991.1

NP_034419.2

Location (UCSC) Chr 6: 89.89 – 89.9 Mb Chr 4: 32.6 – 32.6 Mb
PubMed search [2] [3]
Wikidata
View/Edit HumanView/Edit Mouse

Gap junction alpha-10 protein, also known as connexin-62 (Cx62), is a protein that in humans is encoded by the GJA10 gene.[4]

Connexins, such as GJA10, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits.[4][5]

References

  1. "Drugs that physically interact with Gap junction alpha-10 protein view/edit references on wikidata".
  2. "Human PubMed Reference:".
  3. "Mouse PubMed Reference:".
  4. 1 2 "Entrez Gene: gap junction protein".
  5. Söhl G, Nielsen PA, Eiberger J, Willecke K (2003). "Expression profiles of the novel human connexin genes hCx30.2, hCx40.1, and hCx62 differ from their putative mouse orthologues". Cell Commun. Adhes. 10 (1): 27–36. doi:10.1080/15419060302063. PMID 12881038.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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