Benzamide
Names | |
---|---|
Preferred IUPAC name
Benzamide[1] | |
Other names
Benzoic acid amide Phenyl carboxamide Benzoylamide | |
Identifiers | |
55-21-0 | |
3D model (Jmol) | Interactive image Interactive image |
ChEBI | CHEBI:28179 |
ChEMBL | ChEMBL267373 |
ChemSpider | 2241 |
ECHA InfoCard | 100.000.207 |
EC Number | 200-227-7 |
KEGG | C09815 |
PubChem | 2331 |
RTECS number | CU8700000 |
UNII | 6X80438640 |
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Properties | |
C7H7NO | |
Molar mass | 121.14 g·mol−1 |
Appearance | Off-white solid |
Density | 1.341 g/cm3 |
Melting point | 127 to 130 °C (261 to 266 °F; 400 to 403 K) |
Boiling point | 288 °C (550 °F; 561 K) |
13 g/l | |
Acidity (pKa) | 23.35 (in DMSO) |
Pharmacology | |
N05AL (WHO) | |
Hazards | |
EU classification (DSD) |
Harmful (Xn) |
R-phrases | R22 R40 |
S-phrases | S36/37/39 |
NFPA 704 | |
Flash point | 180 °C (356 °F; 453 K) |
> 500 °C (932 °F; 773 K) | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
verify (what is ?) | |
Infobox references | |
Benzamide is an off-white solid with the chemical formula of C6H5CONH2. It is a derivative of benzoic acid. It is slightly soluble in water, and soluble in many organic solvents.
Chemical derivatives
A number of substituted benzamides exist, including:
- Analgesics
- Ethenzamide
- Salicylamide
- Salverine
- Antidepressants
- Antiemetics/Prokinetics
- Alizapride
- Batanopride
- Bromopride
- Cinitapride
- Cisapride
- Clebopride
- Dazopride
- Domperidone
- Itopride
- Metoclopramide
- Mosapride
- Prucalopride
- Renzapride
- Trimethobenzamide
- Zacopride
- Antipsychotics
- Others
- 3-Aminobenzamide
- Chidamide
- Entinostat
- Eticlopride
- Mocetinostat
- Raclopride
- Procarbazine
- Denipride
- Pyramide (pyridinyl ethylbenzimide)[2]
See also
References
- ↑ Nomenclature of Organic Chemistry : IUPAC Recommendations and Preferred Names 2013 (Blue Book). Cambridge: The Royal Society of Chemistry. 2014. p. 841. doi:10.1039/9781849733069-FP001. ISBN 978-0-85404-182-4.
- ↑ Singh, K. N. & Merchant, Kavita (2012). "The Agrochemical Industry, Annex 17.1". In Kent, James A. Handbook of Industrial Chemistry and Biotechnology. New York: Springer Verlag. pp. 643–698 page 693. doi:10.1007/978-1-4614-4259-2_17.
External links
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