Codeine methylbromide
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| Clinical data | |
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| AHFS/Drugs.com | Monograph |
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| Identifiers | |
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| Synonyms | Codeine bromomethylate, 125-27-9, DEA No. 9070 |
| CAS Number | 125-27-9 |
| PubChem (CID) | 5362447 |
| ChemSpider | 4515039 |
| Chemical and physical data | |
| Formula | C19H24BrNO3 |
| Molar mass | 394.30 g/mol |
| 3D model (Jmol) | Interactive image |
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Codeine methylbromide (Eucodin) is the bromomethane (methylbromide) salt of codeine. Its possession is prohibited in many jurisdictions. It is considered a Schedule I controlled substance in the United States, with a DEA ACSCN of 9070 and nil annual aggregate manufacturing quota.[1] as of 2014. As it is used in a different way than basic salts of codeine like the phosphate or hydrochloride owing to its below-mentioned dual action, it is considered to be a different drug related to codeine rather than merely a salt of it in many contexts. [2]
Also known by the genericised trade name eucodeine, and the salt name also somtimes given as methobromide, this drug was first synthesised in Austria-Hungary in 1903. As it is a bromide in addition to a codeine salt, it has a dual mechanism of action and is indicated for pain with insomnia or nervousness and violent coughing. [3] This codeine-based bromide also has morphine, dihydrocodeine, dihydromorphine, hydromorphone, isocodeine, hydrocodone, and other such analogues; also, there are codeine-based barbiturates and salicylates. [4]