Arctiin
Names | |
---|---|
IUPAC name
(3R,4R)-4-[(3,4-dimethoxyphenyl)methyl]-3-{[3-methoxy-4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]methyl}oxolan-2-one | |
Identifiers | |
20362-31-6 | |
3D model (Jmol) | Interactive image |
ChEMBL | ChEMBL388452 |
ChemSpider | 90827 |
MeSH | arctigenin |
PubChem | 100528 |
| |
| |
Properties | |
C27H34O11 | |
Molar mass | 534.56 g·mol−1 |
Melting point | 110 to 112 °C (230 to 234 °F; 383 to 385 K) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
verify (what is ?) | |
Infobox references | |
Arctiin is a lignan found in many plants of the Asteraceae family, particularly the greater burdock (Arctium lappa) and Centaurea imperialis, and in Trachelospermum asiaticum, Saussurea heteromalla,[1] and Forsythia viridissima.[2] It is the glucoside of arctigenin.
Arctiin and arctigenin have shown anticancer effects in animal research. They have been found to act as agonists of the adiponectin receptor 1.[3]
References
- ↑ Arvind Saklani; Manas Ranjan Sahoo; Prabhu Dutt Mishra; Ram Vishwakarma (2010). Indian Journal of Chemistry (PDF). 50B. India: NISCAIR-CSIR. p. 624. ISSN 0975-0983. Retrieved on April 25, 2011.
- ↑ David J. Triggle; C. R. Ganellin; F. MacDonald (1996). Dictionary of Pharmacological Agents. 1. Boca Raton: Chapman & Hall/CRC. p. 172. ISBN 0-412-46630-9. Retrieved on September 14, 2008 through Google Book Search.
- ↑ Sun Y, Zang Z, Zhong L, Wu M, Su Q, Gao X, Zan W, Lin D, Zhao Y, Zhang Z (2013). "Identification of adiponectin receptor agonist utilizing a fluorescence polarization based high throughput assay". PLoS ONE. 8 (5): e63354. doi:10.1371/journal.pone.0063354. PMC 3653934. PMID 23691032.
External links
- Arctiin entry in the public domain NCI Dictionary of Cancer Terms
This article incorporates public domain material from the U.S. National Cancer Institute document "Dictionary of Cancer Terms".
This article is issued from Wikipedia - version of the 10/17/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.