TGFβ superfamily receptor

Not to be confused with TGFβ receptor.

Transforming growth factor beta (TGFβ) superfamily receptors are a family of serine/threonine kinase receptors that bind members of the TGFβ superfamily of growth factor and cytokine signaling proteins such as TGFβs (TGFβ1, TGFβ2, TGFβ3), bone morphogenetic proteins (BMPs), growth differentiation factors (GDFs), activin and inhibin, myostatin, anti-Müllerian hormone (AMH), and nodal.

TGFβ superfamily receptors

TGFβ superfamily receptors are grouped into three types, type I, type II, and type III. There are seven type I receptors, termed the activin-like receptors (ALK1–7), five type II receptors, and one type III receptor, for a total of 13 TGFβ superfamily receptors.[1][2]

Type I

Type II

Type III

References

  1. ↑ Fliesler SJ, Kisselev OG (26 December 2007). Signal Transduction in the Retina. CRC Press. pp. 273–. ISBN 978-1-4200-0716-9.
  2. ↑ Thiriet M (14 December 2011). Signaling at the Cell Surface in the Circulatory and Ventilatory Systems. Springer Science & Business Media. pp. 666–. ISBN 978-1-4614-1991-4.


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